IP Library Granted Patent US 10,549,274
Granted Patent B2
US 10,549,274 · App. 15/519,659 · Granted Feb 4, 2020

Electrical device with detachable components

Inventors: Clive Gavin Brown (Cambridge, GB); Jason Robert Hyde (Oxford, GB); Mark David Jackson (Oxford, GB); Paul Raymond Mackett (Oxford, GB); Jonathan Edward McKendry (Oxford, GB); Richard Kenneth John Wiltshire (Oxford, GB)
Assignee: Oxford Nanopore Technologies Ltd.
B01L3/502715B01L3/50857B01L2200/04B01L2200/12B01L2300/0645B01L2300/161
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Quick Facts
Patent No.
US 10,549,274
App. No.
15/519,659
Granted
Feb 4, 2020
Kind
B2
Abstract

A detachable electrical device can be formed from a kit comprising a pair of component parts adapted for connection to each other, wherein the connected components of the device may be subsequently disconnected, comprising: an array of electrical connectors, each electrical connector comprising an electrically conductive liquid; and an array of electrodes; wherein the arrays can be brought into contact with each other so as to provide a plurality of electrical connections between the electrically conductive liquid of the array of electrical connectors and the electrodes of the array of electrodes, and wherein the electrical connections may be subsequently broken by detaching the electrically conductive liquid from the electrodes of the array.

Claims (34)

1. A kit comprising a pair of component parts adapted for connection to each other to provide a detachable electrical device, wherein the connected components of the device may be subsequently disconnected, comprising:

an array of electrical connectors, each electrical connector comprising an ionic liquid and/or an ionic solution as an electrically conductive liquid; and

an array of electrodes;

wherein the arrays can be brought into contact with each other so as to provide a plurality of electrical connections between the ionic liquid and/or ionic solution of the array of electrical connectors and the electrodes of the array of electrodes, and wherein the electrical connections may be subsequently broken by detaching the ionic liquid and/or ionic solution from the electrodes of the array;

wherein the array of electrical connectors and the array of electrodes are respectively provided in a first body and a second body; and

wherein the first body and the second body comprise alignment means so as to substantially prevent lateral movement between a surface of the first body and a surface of the second body when the electrical connections are formed.

2. A kit according to claim 1 wherein the interface resistance between the array of electrical connectors and the array of electrodes, when the electrical connections are formed, is 1% or less than the total resistance in the overall electric circuit.

3. A kit according to claim 1 , wherein the electrically conducting liquid comprises a gel.

4. A kit according to claim 1 , wherein the circuit resistance between each of the electrical connectors of the array and each of the respective electrodes of the array of electrodes, when the electrical connections are formed, is greater than 1 MΩ.

5. A kit according to claim 4 , wherein the interface resistance between an electrical connector and an electrode of the array when connected is between 0.1 MΩ and 10 MΩ.

6. A kit according to claim 1 , wherein the array of electrical connectors and the array of electrodes each have a pitch of 1 mm or less.

7. A kit according to claim 1 , wherein the number of electrodes of the array is greater than 100.

8. A kit according to claim 1 , wherein the electrodes are provided at a surface of the second body.

9. A kit according to claim 1 , wherein the first body and/or the second body comprises a flow barrier to substantially prevent the flow of the electrically conducting liquid between the electrodes of the array of electrodes when the electrical connections are formed.

10. A kit according to claim 1 , wherein the second body comprises an integrated circuit.

11. A kit according to claim 1 , wherein the array of electrical connectors is disposed in an array of capillaries.

12. A kit according to claim 11 wherein each of the capillaries of the array comprises a constriction.

13. A kit according to claim 12 , wherein the first body comprises one more electrodes so as to provide a plurality of capillary ionic flow paths through the electrically conducting liquid between the one or more electrodes and electrodes of the array of electrodes, when connected to provide an electrical circuit.

14. A kit according to claim 13 , wherein the one or more electrodes is an electrode that is common to the plurality of flow paths.

15. A kit according to claim 12 , wherein the first body comprises a plurality of nanopores, wherein each nanopore is provided in an insulating substrate provided across the ionic flow path such that current is passed between the electrically conducting liquid and the one of more electrodes through the nanopores.

16. A kit according to claim 15 wherein the insulating substrate is an amphiphilic membrane.

17. A detachable electrical device assembled from a kit according to claim 1 .

18. A detachable electrical device according to claim 17 for characterizing an analyte.

19. A detachable device according to claim 17 , further comprising:

a housing in which the component parts are located;

and wherein the housing is actuatable to connect and disconnect the component parts so as to create and break, respectively, said plurality of electrical connections.

20. A detachable device according to claim 19 , wherein:

the housing further comprising an alignment means for aligning the component parts as they are connected so as to create said plurality of electrical connections.

21. An array of electrodes for use in the kit of claim 1 , wherein a surface between electrodes is hydrophobic compared to the electrodes.

22. A method of connecting an electrical device, the method comprising:

providing an array of electrical connectors wherein each electrical connector comprises an ionic liquid and/or an ionic solution as an electrically conductive liquid;

providing an array of electrodes;

bringing the first and second arrays into contact to form a plurality of electrical connections between respective electrodes of the array and the ionic liquid and/or ionic solution; and

separating the electrically conducting liquid from the electrodes of the array of electrodes in order to break the electrical connections.

Assignments (2)
CHANGE OF NAME Recorded Aug 8, 2023
From: OXFORD NANOPORE TECHNOLOGIES LIMITED
To: OXFORD NANOPORE TECHNOLOGIES PLC
Reel/Frame 064522/0166 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 2, 2017
From: BROWN, CLIVE GAVIN; HYDE, JASON ROBERT; JACKSON, MARK DAVID; MACKETT, PAUL RAYMOND; MCKENDRY, JONATHAN EDWARD; WILTSHIRE, RICHARD KENNETH JOHN
To: OXFORD NANOPORE TECHNOLOGIES LTD.
Reel/Frame 043171/0704 →
Priority Claims (3)
GB 1418512.8 · Oct 17, 2014 · national
GB 1507904.9 · May 8, 2015 · national
GB 1508158.1 · May 13, 2015 · national
Continuity (1)
Related Publication 20170326550A1 · Nov 16, 2017
Cited By (7)
US 12,350,637 US 12,392,766 US 12,411,125 US 12,458,945 US 12,540,937 US 12,552,661 US 12,667,839