Compositions and methods for improving human health and nutrition
The present invention provides compositions and methods of promoting human health and nutrition.
1. A composition comprising:
a. inulin,
b. a probiotic comprising a mixture of Pediococcus acidilactici, Pediococcus pentosaceus , and Lactobacillus plantarum microorganisms produced by submerged liquid fermentation,
c. a postbiotic derived from the liquid fermentation medium of the Pediococcus acidilactici, Pediococcus pentosaceus , and Lactobacillus plantarum microorganisms, wherein the postbiotic is prepared by:
i. collecting the supernatants from the centrifugation of each of the individual anaerobic fermentations of the Pediococcus acidilactici, Pediococcus pentosaceus , and Lactobacillus plantarum organisms;
ii. mixing the supernatants together;
iii. freeze-drying the mixed supernatants to a moisture content less than about 5% by weight and
iv. grinding the dried supernatants of step (iii) to a mean particle size of 295 microns, with 60% of the mixture in the size range between 175-900 microns,
d. moringa,
e. Boswellia extract, and
f. fiber.
2. A method of improving human health in a subject, the method comprising orally administering to the subject the composition of claim 1 .
3. The composition of claim 1 , comprising at least 1% of inulin by weight.
4. The composition of claim 1 , comprising at least 1% of the probiotic by weight.
5. The composition of claim 1 , comprising at least 1% of the postbiotic by weight.
6. The composition of claim 1 , formulated into a chewable food, skin cream, lotion, gel, or ointment.
7. The composition of claim 1 , wherein the concentration of the Pediococcus acidilactici, Pediococcus pentosaceus , and Lactobacillus plantarum microorganisms is between 10 9 and 10 11 CFU per gram of the mixture.
8. The method of claim 2 , wherein the composition is administered as a tablet, capsule, powder, or granulate.
9. The method of claim 8 , wherein the tablet, capsule, powder or granulate contains between about 5-800 milligrams of the composition.
10. A method for treating a digestive disorder in a subject, the method comprising orally administering to the subject the composition of claim 1 .
11. The method of claim 10 , wherein the digestive disorder is constipation, diarrhea dysbiosis, Crohn's disease, food allergy, lactose intolerance pouchitis, or ulcerative colitis.
12. A method for reducing comorbidities associated with Metabolic Syndrome X in a subject, the method comprising orally administering to the subject the composition of claim 1 .
13. A method for treating a skin disorder in a subject, the method comprising topically administering to the subject the composition of claim 6 .
14. The method of claim 13 , wherein the skin disorder is rosacea, acne, psoriasis, eczema, or dermatitis.
15. A method for improving wound healing in a subject having a wound, the method comprising administering to the wound the composition of claim 6 .