IP Library Granted Patent US 11,364,254
Granted Patent B2
US 11,364,254 · App. 16/561,990 · Granted Jun 21, 2022

Compositions and methods using a polyphenol for musculoskeletal health

Inventors: Marie Noelle Horcajada (Echenevex, FR); Fanny Membrez (Cugy, CH); Denis Breuille (Lausanne, CH); Claire Boutry (Corcelles pres Concise, CH)
Assignee: Societe des Produits Nestle S.A.
A61K31/7048A23L33/105A23L33/12A23L33/17A23L33/19A23L33/40A61K31/12A61K31/202A61K31/352A61K31/353A61K38/1709A61K45/06A23V2002/00A61K38/00
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Quick Facts
Patent No.
US 11,364,254
App. No.
16/561,990
Granted
Jun 21, 2022
Kind
B2
Abstract

A composition comprising one or more polyphenols, such as oleuropein, rutin, curcumin or quercetin, can treat or prevent sarcopenia, reduce a loss of muscle functionality (e.g. muscle strength, gait speed, etc.), increase muscle functionality, and/or improve recovery of muscle functionality after muscle atrophy. The composition can be administered to an individual who is elderly and/or frail.

Claims (9)

1. A method of reducing a loss of muscle functionality, increasing muscle functionality and/or improving recovery of muscle functionality after muscle atrophy in an individual in need thereof, the method comprising administering to the individual a composition comprising (i) 0.01 mg to about 1.0 g of oleuropein per serving as the only polyphenol, (ii) a fatty acid, (iii) branched chain amino acids comprising leucine, isoleucine and valine, (iv) 800 to 1200 IU of Vitamin D per serving, and (v) whey protein, wherein the composition is administered in a daily amount comprising 5 g to 50 g of the whey protein per day.

2. The method of claim 1 , wherein the composition further comprises an additional polyphenol selected from the group consisting of rutin, quercetin, curcumin and combinations thereof.

3. The method of claim 1 , wherein the fatty acid is an n-3 fatty acid.

4. The method of claim 1 , wherein the composition further comprises a protein selected from the group consisting of casein, pea protein, soy protein and combinations thereof.

5. The method of claim 1 , wherein the individual has sarcopenia.

6. The method of claim 1 , wherein the muscle functionality comprises a characteristic selected from the group consisting of muscle strength, gait speed, and combinations thereof.

7. The method of claim 1 , wherein the individual is an elderly having mobility issues or muscle weakness.

8. The method of claim 1 , wherein the method consists of the administering of the composition.

9. The method of claim 1 , wherein the composition is administered to the individual for a time period comprising at least 30 consecutive days.

Assignments (2)
MERGER Recorded Apr 5, 2022
From: NESTEC S.A.
To: SOCIETE DES PRODUITS NESTLE S.A.
Reel/Frame 059501/0382 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 5, 2022
From: HORCAJADA, MARIE NOELLE; MEMBREZ, FANNY; BREUILLE, DENIS; BOUTRY, CLAIRE
To: NESTEC S.A.
Reel/Frame 059616/0374 →
Continuity (3)
Division 15776451
Provisional Application 62256401 · Nov 17, 2015
Related Publication 20200061094A1 · Feb 27, 2020
Cited By (1)
US 12,708,639