Tumor ablation device and related systems and methods
Tumor ablation devices and related systems and methods are disclosed. Some tumor ablation devices include an RF energy delivery probe with two conductors and one or more thermocouples. The thermocouple measures a temperature at a location on one of the conductors. A generator can produce a current to be conducted between the first conductor and the second conductor via tissue within a desired ablation region. The ablation regions created by the RF energy delivery probe are symmetric about poles of the first conductor and the second conductor. A distal portion of the RF energy delivery probe may articulate, enabling a user to position the RF energy delivery probe in a proper position to ablate the tumor. The thermocouples may be disposed on a flexible or wired thermocouple circuit that is disposed between insulators.
1. A system for tumor ablation, the system comprising:
a first probe comprising:
a first conductor;
a second conductor disposed distal to the first conductor;
an insulator bushing disposed between the first conductor and the second conductor;
a distal thermocouple to measure a temperature at a location on the second conductor;
a plurality of thermocouples that are disposed between the first conductor and the second conductor; and
a generator to produce a current to be conducted between the first conductor and the second conductor to create an ablation region;
wherein the system is configured to create a symmetric ablation region.
2. The system for tumor ablation of claim 1 , wherein the plurality of thermocouples are disposed proximal to the insulator bushing.
3. The system for tumor ablation of claim 1 , wherein the plurality of thermocouples are evenly spaced.
4. The system for tumor ablation of claim 1 , wherein the first probe further comprises a first insulator and a second insulator disposed radially between the first conductor and the second conductor, and wherein the plurality of thermocouples are disposed radially and longitudinally between the first insulator and the second insulator.
5. The system for tumor ablation of claim 1 , wherein the plurality of thermocouples and the distal thermocouple are disposed on a flexible thermocouple circuit.
6. The system for tumor ablation of claim 5 , wherein the flexible thermocouple circuit comprises at least two tails, wherein the plurality of thermocouples are disposed on a first tail and the distal thermocouple is disposed on a second tail, and wherein the second tail extends along the center of an inner diameter of the second conductor to a distal portion of the second conductor.
7. The system for tumor ablation of claim 1 , wherein a distal portion of the first probe is configured to articulate relative to a proximal portion of the first probe.
8. The system for tumor ablation of claim 1 , wherein the system further comprises a remote that manually controls the energy delivered to the first probe.
9. The system for tumor ablation of claim 1 , wherein the system is configured to create a 1 cm symmetric ablation region.
10. The system for tumor ablation of claim 1 , wherein the system is configured to create a 3.5 cm symmetric ablation region.
11. The system for tumor ablation of claim 1 , wherein the generator further comprises a first port and a second port, wherein the first probe is configured to couple to the first port and a second probe is configured to couple to the second port.
12. The system for tumor ablation of claim 11 , wherein the first port comprises a first indicia and the second port comprises a second indicia,
wherein the first probe comprises a third indicia and the second probe comprises a fourth indicia, and
wherein the first indicia corresponds with the indicia of the probe that is coupled to the first port and the second indicia corresponds with the indicia of the probe that is coupled to the second port.
13. An RF energy delivery probe for tumor ablation comprising:
a first tubular conductor;
a second tubular conductor partially disposed within the first tubular conductor and disposed such that a distal portion of the second conductor is distal to the first conductor;
an insulator bushing disposed between the first conductor and the second conductor; and
a distal thermocouple disposed at a distal end of the second tubular conductor to measure a temperature at the distal end of the probe;
a plurality of thermocouples disposed between the first tubular conductor and the second tubular conductor and proximal to the distal thermocouple,
wherein the RF energy delivery probe is configured to create an ablation region.
14. The RF energy delivery probe of claim 13 , further comprising a first insulator and a second insulator disposed radially between the first conductor and the second conductor, and wherein the plurality of thermocouples are disposed between the first insulator and the second insulator.
15. The RF energy delivery probe of claim 13 , wherein a distal portion of the RF energy delivery probe is configured to articulate relative to a proximal portion of the probe.
16. The RF energy delivery probe of claim 13 , wherein the distal portion of the second tubular conductor is configured to extend and retract in the longitudinal direction of the RF energy delivery probe relative to the first tubular conductor.
17. The RF energy delivery probe of claim 13 , wherein the plurality of thermocouples and the distal thermocouple are disposed on a flexible thermocouple circuit.
18. The system for tumor ablation of claim 17 , wherein the flexible thermocouple circuit comprises at least two tails, wherein the plurality of thermocouples are disposed on a first tail and the distal thermocouple is disposed on a second tail, and wherein the second tail extends along the center of an inner diameter of the second tubular conductor to a distal portion of the second tubular conductor.
19. A method of ablating tumors in a patient, comprising:
inserting a first RF energy delivery probe within a patient to a tumor location, wherein the RF energy delivery probe comprises:
a first conductor,
a second conductor disposed distal to the first conductor; and
an insulator bushing disposed between the first conductor and the second conductor; and
a plurality of thermocouples that are disposed between the first conductor and the second conductor;
producing a current between the first conductor and the second conductor to create a symmetric ablation zone; and
measuring a temperature at a point on the second conductor.