IP Library Granted Patent US 11,123,315
Granted Patent B2
US 11,123,315 · App. 16/745,093 · Granted Sep 21, 2021

Topical compositions for pain relief, manufacture and use

Inventors: Philip J. Birbara (West Hartford, CT); Daniel Bucks (Millbrae, CA)
Assignee: Propella Therapeutics, Inc.
A61K31/165A61K9/0014A61K9/06A61K9/08A61K31/00A61K31/045A61K31/05A61K31/125A61K31/618A61K31/728A61K45/06A61K47/10A61K47/26A61K47/36A61K47/42A61K47/44
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Quick Facts
Patent No.
US 11,123,315
App. No.
16/745,093
Granted
Sep 21, 2021
Kind
B2
Abstract

The present invention relates to TRPV1 selective agonist compositions including a capsaicinoid, a surfactant and an extended release agent, and to methods of manufacture and methods of providing pain relief as well as treating a variety of disorders with such compositions.

Claims (5)

1. A composition comprising:

i) 0.075-20% by weight of a capsaicinoid,

ii) an extended release agent to slow the release of said capsaicinoid from said composition upon administration of said composition to a mammal, and

iii) a surfactant,

wherein said composition reduces or eliminates the burning and stinging created by said capsaicinoid upon topical administration.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 25, 2025
From: ASTELLAS US LLC
To: JIANGSU AOSAIKANG PHARMACEUTICAL CO., LTD.
Reel/Frame 072378/0590 →
MERGER Recorded Nov 15, 2024
From: PROPELLA THERAPEUTICS, INC.
To: ASTELLAS US LLC
Reel/Frame 069281/0486 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2020
From: BIRBARA, CAROL; BUCKS, DANIEL
To: VIZURI HEALTH SCIENCES LLC
Reel/Frame 052956/0750 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 15, 2020
From: VIZURI HEALTH SCIENCES LLC
To: PROPELLA THERAPEUTICS, INC.
Reel/Frame 052939/0276 →
Continuity (5)
Continuation 16243317 · Jan 9, 2019
Continuation 15939445 · Mar 29, 2018
Division 14687566 · Apr 15, 2015
Provisional Application 61979905 · Apr 15, 2014
Related Publication 20200323800A1 · Oct 15, 2020