Granted Patent B2

US 10,994,157 · App. 16/796,608 · Granted May 4, 2021

Inventors: Angela M. Christiano (Mahwah, NJ); Raphael Clynes (West Nyack, NY)

Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

A61Q7/00A61K8/41A61K8/4953A61K8/64A61K31/137A61K31/277A61K31/407A61K31/437A61K31/506A61K31/519A61K31/52A61K31/529A61K31/5377A61K31/553A61K31/63A61K31/7052A61K31/713A61K2800/782

Abstract

Claims (11)

1. A method of treating a hair-loss disorder in a human in need thereof comprising orally administering to the human an effective amount of a janus kinase (JAK) inhibitor having the following structure:

in a pharmaceutical composition selected from a capsule, a tablet, a pill, and a troche, wherein the hair-loss disorder is alopecia areata.

2. The method of claim 1 , wherein the alopecia areata is alopecia totalis.

3. The method of claim 1 , wherein the alopecia areata is alopecia universalis.

4. A method of treating a hair-loss disorder in a human in need thereof comprising orally administering once daily or twice daily to the human an effective amount of a j anus kinase (JAK) inhibitor having the following structure:

in a pharmaceutical composition, wherein the hair-loss disorder is alopecia areata.

5. The method of claim 4 , wherein the alopecia areata is alopecia totalis.

6. The method of claim 4 , wherein the alopecia areata is alopecia universalis.

7. The method of claim 4 , wherein the pharmaceutical composition is selected from a capsule, a tablet, a pill, and a troche.

8. The method of claim 4 , wherein the pharmaceutical composition is orally administered once daily.

9. The method of claim 4 , wherein the pharmaceutical composition is orally administered twice daily.

Assignments (1)

Continuity (10)