Pharmaceutical compositions comprising perillyl alcohol derivatives
A pharmaceutical composition is provided which includes perillyl alcohol conjugated with a therapeutic agent and further includes and a hydrolyzable acylated aliphatic tail. A method of using the pharmaceutical composition is also provided for treating a condition or disease of a patient, e.g., cancer.
1. A pregabalin perillyl alcohol (POH) linoleate triple conjugate compound.
2. A valaciclovir perillyl alcohol (POH) linoleate triple conjugate compound.
3. A lamivudine perillyl alcohol (POH) linoleate triple conjugate compound, or an abacavir perillyl alcohol (POH) linoleate triple conjugate compound.
4. A pharmaceutical composition comprising the compound of claim 1 .
5. A pharmaceutical composition comprising the compound of claim 2 .
6. A pharmaceutical composition comprising the compound of claim 3 .