IP Library Granted Patent US 10,850,130
Granted Patent B2
US 10,850,130 · App. 16/905,261 · Granted Dec 1, 2020

Neutron source for neutron capture therapy

Inventors: Melvin Arthur Piestrup (Redwood City, CA); Craig Mathew Brown (Santa Clara, CA); Allan Xi Chen (Daly City, CA); Charles Kevin Gary (Palo Alto, CA); Yao Zong Guan (San Francisco, CA); Yoshio Horii (Fukushima, JP); Glenn Emerson Jones, Jr. (Pittsburg, CA); Yuji Kokubo (Fukushima, JP); Naoyuki Yamada (Fukushima, JP); Shotaro Komura (Fukushima, JP)
Assignee: Adelphi Technology, Inc.
A61N5/1077A61N5/10G21G4/02A61N2005/109A61N2005/1094A61N2005/1095
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Quick Facts
Patent No.
US 10,850,130
App. No.
16/905,261
Granted
Dec 1, 2020
Kind
B2
Abstract

A Boron neutron cancer treatment system has a central treatment chamber for a subject, with six substantially identical neutron generators each having an acceleration chamber, the generators positioned around a secondary moderator with the axis of each acceleration chamber passing through center of the treatment chamber, and with angled sides of the neutron generators fully adjacent.

Claims (8)

1. A Boron neutron cancer treatment system, comprising:

a secondary moderator having a central treatment chamber for a subject; and six neutron generators, each comprising a pre-moderator block of moderating material having an upper surface, a lower surface, a first and a second end, opposite side surfaces angled inward by thirty degrees along at least a portion of the height, a first length, a first width less than the first length, and a first thickness, a cylindrical acceleration chamber having a first diameter the first width of the pre-moderator block, sealed at one end to the upper surface of the pre-moderator block adjacent the first end of the pre-moderator block, with a vertical axis perpendicular to the upper surface, the acceleration chamber having a height and a top cover at a second end away from the pre-moderator block, a vacuum pump engaging the acceleration chamber at a right angle to the vertical axis, evacuating the acceleration chamber to a high vacuum, a plasma ion chamber opening into the acceleration chamber through an ion extraction iris through the top cover of the acceleration chamber on the vertical axis of the acceleration chamber, a gas source providing deuterium gas to the plasma ion chamber, a microwave energy source ionizing the gas in the plasma ion chamber, a cylindrical primary isolation well extending a distance into the pre-moderator block from the upper surface, centered on the vertical axis of the acceleration chamber, a secondary isolation well in a shape of a hollow cylinder surrounding the primary isolation well, to a depth somewhat less than the distance of the primary isolation well, within the first diameter of the acceleration chamber, a water-cooled titanium target disk having a target surface orthogonal to the axis of the acceleration chamber, the target disk having a diameter smaller then a diameter of the isolation well, positioned at a lower extremity of the isolation well, the target disk biased to a negative DC voltage, and electrically grounded metal cladding covering all otherwise exposed surfaces of the pre-moderator block;

wherein the six neutron generators are positioned around the secondary moderator with the axis of each acceleration chamber passing through the center of the treatment chamber, and with the angled sides of the neutron generators fully adjacent.

2. The system of claim 1 further comprising six rectangular spacing blocks of moderator material, one spacer block placed between each adjacent neutron generator with sides of the spacer blocks fully adjacent with the angled sides of the neutron generators.

3. The system of claim 1 wherein the secondary moderator is shaped to fill all volume between the neutron generators and the central treatment chamber.

4. The system of claim 1 wherein the secondary moderator is a block or blocks of solid moderator material.

5. The system of claim 2 wherein the secondary moderator is a container filled with heavy water.

6. The system of claim 2 wherein the secondary moderator is a container filled with granulated moderator material.

Continuity (7)
Division 16662523 · Oct 24, 2019
Continuation In Part 15488983 · Apr 17, 2017
Continuation 14190389 · Feb 26, 2014
Continuation 13532447 · Jun 25, 2012
Provisional Application 61571406 · Jun 27, 2011
Provisional Application 62749875 · Oct 24, 2018
Related Publication 20200316405A1 · Oct 8, 2020
Cited By (1)
US 12,245,355