IP Library › Granted Patent US 11,753,365
Granted Patent B2
US 11,753,365 · App. 17/199,860 · Granted Sep 12, 2023

Methods of treating fibrosis

Inventors: Sergio Baroni (Villa d'adda, IT); Salvatore Bellinvia (Mendrisio, CH); Francesca Viti (Mendrisio, CH)
Assignee: Nogra Pharma Limited
C07C229/44A61K31/196A61K31/343A61K31/357A61P1/04
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Quick Facts
Patent No.
US 11,753,365
App. No.
17/199,860
Granted
Sep 12, 2023
Kind
B2
Abstract

The present disclosure is directed in part to methods of treating fibrosis, e.g., hepatic fibrosis and/or intestinal fibrosis, comprising administering to a patient in need thereof an effective amount of a disclosed compound.

Claims (8)

1. A method of treating hepatic fibrosis, the method comprising administering to a patient in need thereof, a therapeutically effective amount of 2-methoxy-3-(4′-aminophenyl) propionic acid, or a pharmaceutically acceptable salt and/or a stereoisomer thereof.

2. A method of treating hepatic fibrosis, the method comprising administering to a patient in need thereof, a pharmaceutical preparation comprising a therapeutically effective amount of 2-methoxy-3-(4′-aminophenyl) propionic acid, or a pharmaceutically acceptable salt and/or a stereoisomer thereof.

3. The method of claim 2 , wherein the pharmaceutical preparation is administered orally.

4. The method of claim 2 , wherein the patient is human.

5. The method of claim 2 , wherein the 2-methoxy-3-(4′-aminophenyl)propionic acid is (S)-2-methoxy-3-(4′-aminophenyl)propionic acid, or a pharmaceutically acceptable salt thereof.

6. The method of claim 1 , wherein the 2-methoxy-3-(4′-aminophenyl)propionic acid is (S)-2-methoxy-3-(4′-aminophenyl)propionic acid, or a pharmaceutically acceptable salt thereof.

7. The method of claim 1 , wherein the administering is orally.

8. The method of claim 1 , wherein the patient is human.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 19, 2023
From: BARONI, SERGIO; BELLINVIA, SALVATORE; VITI, FRANCESCA
To: NOGRA PHARMA LIMITED
Reel/Frame 064318/0001 →
Priority Claims (1)
EP 12425027 · Feb 9, 2012 · regional
Continuity (4)
Continuation 15593864 · May 12, 2017
Division 14377362
Provisional Application 61644544 · May 9, 2012
Related Publication 20220033346A1 · Feb 3, 2022
Cited By (2)
US 12,291,494 US 12,509,416