IP Library › Granted Patent US 12,528,913
Granted Patent B2
US 12,528,913 · App. 17/327,952 · Granted Jan 20, 2026

Antimicrobial anhydrous topical skin closure compositions and systems

Inventors: Duan Li Ou (Warren, NJ); Leo Kriksunov (Ithaca, NY); Julian Quintero (Flemington, NJ)
Assignee: Ethicon, Inc.
C08G77/08A61K31/085A61L26/0004A61L26/0066C08G77/12C08G77/20C08K5/0058C08K5/5419A61L2300/202C08G2170/40C08G2340/00C08K5/10
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Quick Facts
Patent No.
US 12,528,913
App. No.
17/327,952
Granted
Jan 20, 2026
Kind
B2
Abstract

Novel compositions and systems for closure of wounds with antimicrobial effectiveness are disclosed. The compositions provide devices of improved flexibility and elasticity and are readily applied to wound sites or over wound closure devices. The present invention is also directed to a novel platinum catalyst for use in such compositions. The catalyst provides for rapid curing on topical surfaces such as skin and bonds to such surfaces in about 2-5 minutes.

Claims (12)

1 . A composition comprising:

a cross-linkable silicone polymer having reactive functionalities;

a silica-containing composition;

a silicone crosslinking agent;

a catalyst, wherein said catalyst comprises a platinum tetramethyldivinyl disiloxane diethyl maleate complex having the formula:

Pt[(CH 2 ═CH)(CH 3 ) 2 Si] 2 O·(COCH═CHCO)(C 2 H 5 O) 2 ; and

a wound moisture absorbent and/or indicator, wherein said wound moisture absorbent and/or indicator is selected from the group consisting of superabsorbent silica and an anhydrous inorganic salt.

2 . A kit comprising:

a) a wound closure device; and

b) the composition of claim 1 .

3 . The kit of claim 2 , wherein the wound closure device is a wound closure strip.

4 . The kit of claim 3 , wherein the wound moisture absorbent and/or indicator in applied or coated on the wound closure strip.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2022
From: OU, DUAN LI; KRIKSUNOV, LEO; QUINTERO, JULIAN
To: ETHICON, INC.
Reel/Frame 061510/0232 →
Continuity (2)
Continuation In Part 16885366 · May 28, 2020
Related Publication 20210371596A1 · Dec 2, 2021
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