Granted Patent B2

US 12,465,577 · App. 16/885,366 · Granted Nov 11, 2025

Inventor: Duan Li Ou (Warren, NJ)

Assignee: Ethicon, Inc.

A61K9/7084A61K31/09A61K31/155A61K31/444A61K33/38A61K47/34

Abstract

Claims (22)

1 . A composition comprising:

a cross-linkable silicone polymer having reactive functionalities;

a silica-containing composition comprising a trimethyl silyl surface treated silica filler;

a silicone cross-linking agent;

a catalyst, wherein said catalyst comprises a platinum tetramethyldivinyl disiloxane diethyl maleate complex having the formula:

Pt[(CH 2 ═CH)(CH 3 ) 2 Si] 2 O·(COCH=CHCO)(C 2 H 5 O) 2 ; and

an antimicrobial agent.

2 . The composition of claim 1 , wherein the cross-linkable silicone polymer is selected from the group consisting of vinyl terminated polydialkylsiloxane, vinyl terminated polydimethylsiloxane, vinyl terminated polydiphenylsilane-dimethylsiloxane copolymer, vinyl terminated polyphenylmethylsiloxane, vinyl terminated polyfluoropropylmethyl-dimethylsiloxane copolymer, vinyl terminated polydiethylsiloxane, and SiH terminated polydimethyldisiloxane.

3 . The composition of claim 1 , wherein the cross-linkable silicone polymer comprises vinyl terminated polydimethylsiloxane.

4 . The composition of claim 1 , wherein the silicone cross-linking agent is selected from the group consisting of polymethylhydrosiloxane, polymethylhydro-co-polydimethylsiloxane, polyethyhydrosiloxane, polymethylhydrosiloxane-co-octylmethylsiloxane, and polymethylhydrosiloxane-co-methylphenylsiloxane.

5 . The composition of claim 1 , wherein the silicone cross-linking agent comprises polymethylhydrosiloxane, polymethylhydro-co-polydimethylsiloxane and combinations thereof.

6 . The composition of claim 1 , wherein the composition additionally comprises about 0 wt. % to about 30 wt. % of an organic solvent, based upon the weight of the composition.

7 . The composition of claim 1 , wherein the composition comprises about 1 wt. % to about 15 wt. % of the silicone cross-linking agent based on total solids, wherein the composition additionally comprises about 0 wt. % to about 30 wt. % of an organic solvent, based upon the weight of the composition.

8 . The composition of claim 1 , wherein the composition comprises about 0.003 wt. % to about 0.06 wt. % of the platinum catalyst, based on total solids, wherein the composition additionally comprises about 0 wt. % to about 30 wt. % of an organic solvent, based upon the weight of the composition.

9 . The composition of claim 1 , wherein the composition additionally comprises a solvent selected from the group consisting of pentane, hexane, heptanes, mixtures of low molecular weight olefins, and combinations thereof.

10 . The composition of claim 1 , wherein the antimicrobial agent is selected from the group consisting of triclosan, chlorhexidine, polyhexamethylene biguanide (PHMB), octenidine, elemental silver and silver salts.

11 . The composition of claim 10 wherein the antimicrobial agent is triclosan.

12 . The composition of claim 11 , wherein the triclosan comprises about 0.05 wt. % to about 2.0 wt. % of the composition.

13 . The composition of claim 12 , wherein the triclosan comprises about 0.1 wt. % to about 1.5 wt. % of the composition.

14 . The composition of claim 13 , wherein the triclosan comprises about 0.2 wt. % to about 1.0 wt. % of the composition.

15 . The composition of claim 1 , wherein the composition is curable at temperatures at about 19 C.

16 . The composition of claim 15 , wherein the composition is curable at temperatures of about 28 C in about 2-5 minutes.

Assignments (1)

Continuity (1)

References Cited (192)