IP Library Granted Patent US 11,598,630
Granted Patent B2
US 11,598,630 · App. 17/589,265 · Granted Mar 7, 2023

Method and device for superresolution optical measurement using singular optics

Inventor: Gabriel Y. Sirat (Paris, FR)
Assignee: Bioaxial SAS
G01B11/14G01N21/64G01N21/6428G01N21/6458G02B21/0056G02B21/0072G02B21/0076G02B21/16G01B11/25G01N2201/06113G01N2201/12
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Quick Facts
Patent No.
US 11,598,630
App. No.
17/589,265
Granted
Mar 7, 2023
Kind
B2
Abstract

An optical method of measurement and an optical apparatus for determining the spatial position of at least one luminous object on a sample. A sequence of at least two compact luminous distributions of different topological families is projected onto the sample, and light re-emitted by the at least one luminous object is detected. At least one optical image is generated for each luminous distribution on the basis of the light detected. The optical images are analyzed to obtain spatiotemporal information regarding the light re-emitted by the at least one luminous object, or location of the at least one luminous object.

Claims (11)

1. A method of optical measurement for determining the spatial position of at least one luminous object in a sample, the method comprising:

projecting onto the sample a sequence of a first compact luminous distribution and a second compact luminous distribution, wherein the first and second compact luminous distributions are of different topological families;

formatting, in a manner selected from the group consisting of static and dynamic, the projected sequence of the first and second compact luminous distributions to provide a polarization state configured to mitigate vector effects;

detecting light re-emitted by said at least one luminous object of the sample;

generating from the detected light a first image of the at least one luminous object as illuminated by the first compact luminous distribution and a second image of the at least one luminous object as illuminated by the second compact luminous distribution; and

algorithmically analyzing images to obtain spatial position information of said at least one luminous object.

2. A method according to claim 1 , wherein formatting the projected sequence includes formatting the projected sequence to provide the polarization state in a form that is static and rotationally symmetrical.

3. A method according to claim 2 , wherein formatting the projected sequence includes formatting the projected sequence to provide the polarization state in a form that is circular.

4. A method according to claim 1 , wherein formatting the projected sequence includes formatting the projected sequence to provide the polarization state in a form that is radial.

5. A method according to claim 1 , wherein formatting the projected sequence includes formatting the projected sequence to provide the polarization state in a form that is azimuthal.

6. A method according to claim 1 , wherein formatting the projected sequence includes formatting the projected sequence to provide the polarization state in a form that is dynamic.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2022
From: SIRAT, GABRIEL
To: BIOAXIAL SAS
Reel/Frame 058841/0649 →
Priority Claims (1)
FR 1004067 · Oct 15, 2010 · national
Continuity (6)
Continuation 17087238 · Nov 2, 2020
Continuation 16557030 · Aug 30, 2019
Continuation 15812016 · Nov 14, 2017
Continuation 14998051 · Dec 24, 2015
Continuation 13822355
Related Publication 20220155055A1 · May 19, 2022
Cited By (1)
US 12,203,741