IP Library Granted Patent US 12,691,247
Granted Patent B2
US 12,691,247 · App. 17/726,989 · Granted Jul 28, 2026

Systems and methods for visual cortex targeting and treatment

Inventor: Richard Hanbury (Lafayette, CO)
Assignee: SANA HEALTH INC.
A61M21/02A61M2021/0022A61M2021/0027A61M2021/005A61M2205/3569A61M2205/3592A61M2205/505A61M2209/088
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,691,247
App. No.
17/726,989
Filed
Apr 22, 2022
Granted
Jul 28, 2026
Kind
B2
Art Unit
3791
USPC
600/28
Abstract

Disclosed are systems and methods for a computerized framework that detects medical conditions within patients and dynamically effectuates a treatment. The disclosed framework is configured for controlling computerized medical equipment by analyzing data associated with a patient, determining underlying conditions of the patient, then automatically causing such equipment to output electronic stimuli that can address the medical condition(s) detected. The framework can determine a correlation between a patient's attributes, electronic data of a condition of a patient and a medical disorder, and cause a medical device to treat and monitor improvements of the condition and disorder. The framework can be configured to focus in on particular body parts of a patient that have been identified as a body part that enables treatment as well as a part that facilitates the most efficient treatment for a recovery.

Claims (49)

1 . A method comprising the steps of:

receiving, by a device, a request to provide a medical treatment to a patient, the medical treatment comprising instructions related to electronic stimuli to be output via a therapeutic medical device and delivered to a visual cortex of the patient, the treatment instructions further comprising information identifying at least one eye component of the therapeutic medical device to output the electronic stimuli;

identifying, by the device, a status of the patient, the status of the patient corresponding to a medical condition of the patient;

determining, by the device, a type and value of the electronic stimuli based on the identified status of the patient;

automatically causing, by the device, the therapeutic medical device to adjust a positioning of the at least one eye component based on the identified status and the determined type and value of the electronic stimuli, the adjusted positioning enabling the electronic stimuli to be output via the at least one eye component according to the type and value, the adjusted positioning further enabling the electronic stimuli to be directed to a particular body part of the patient; and

causing the adjusted therapeutic medical device, by the device, to output the electronic stimuli provided in the medical treatment.

2 . The method of claim 1 , further comprising:

determining, by the device, based on the status of the patient and the determined type and value of the electronic stimuli, the particular body part of the patient, wherein the determination of the particular body part is based on the device executing a machine learning (ML) algorithm with the status of the patient and the determined type and value of the electronic stimuli as the input.

3 . The method of claim 2 , wherein the particular body part of the patient is at least one of a sub-part of at least one eye of the patient and a sub-part of the visual cortex of the patient.

4 . The method of claim 3 , wherein the particular body part of the patient corresponds to at least one of a quantity of eyes and dimensions and/or locations of the eyes.

5 . The method of claim 1 , further comprising:

identifying, by the device, a profile of the patient, the profile being an electronic medical record (EMR), the profile comprising information related to the status of the patient; and

analyzing, by the device, the profile, and determining symptoms of the medical condition of the patient.

6 . The method of claim 5 , wherein the identified status of the patient corresponds to the determined symptoms of the medical condition.

7 . The method of claim 5 , wherein the profile comprises information related to at least one of an identity (ID), name, address, age, race, gender, demographic information, geographic information, medical history, prescription history, family medical history, insurance information and collected biometric data of the patient.

8 . The method of claim 1 , wherein the determination of the type and value of the electronic stimuli is based on the device executing a machine learning (ML) algorithm with the status as the input.

9 . The method of claim 1 , further comprising:

receiving, by the device, response data from a targeted portion of the visual cortex of the patient, the response data produced in response to the output of the electronic stimuli;

analyzing, by the device, the response data, and determining information related to the response of the patient; and

storing, by the device, the response data and the determined information in an electronic medical record (EMR) of the patient, wherein the steps of the method are performed by the device executing a machine learning (ML) algorithm trained on the stored response data and determined information for a plurality of patients.

10 . The method of claim 1 , wherein the electronic stimuli is output according to at least one of a pattern, rate, shape, letter, frequency, quantity, volume, intensity, brightness, contrast, current and voltage.

11 . The method of claim 1 , wherein the therapeutic medical device is communicatively coupled to the device.

12 . The method of claim 1 , wherein the device is the therapeutic medical device.

13 . A non-transitory computer-readable storage medium tangibly encoded with computer-executable instructions, that when executed by a device, perform a method comprising steps of:

receiving, by the device, a request to provide a medical treatment to a patient, the medical treatment comprising instructions related to electronic stimuli to be output via a therapeutic medical device and delivered to a visual cortex of the patient, the treatment instructions further comprising information identifying at least one eye component of the therapeutic medical device to output the electronic stimuli;

identifying, by the device, a status of the patient, the status of the patient corresponding to a medical condition of the patient;

determining, by the device, a type and value of the electronic stimuli based on the identified status of the patient;

automatically causing, by the device, the therapeutic medical device to adjust a positioning of the at least one eye component based on the identified status and the determined type and value of the electronic stimuli, the adjusted positioning enabling the electronic stimuli to be output via the at least one eye component according to the type and value, the adjusted positioning further enabling the electronic stimuli to be directed to a particular body part of the patient; and

causing the adjusted therapeutic medical device, by the device, to output the electronic stimuli provided in the medical treatment.

14 . The non-transitory computer-readable storage medium of claim 13 , further comprising:

determining, by the device, based on the status of the patient and the determined type and value of the electronic stimuli, the particular body part of the patient, wherein the determination of the particular body part is based on the device executing a machine learning (ML) algorithm with the status of the patient and the determined type and value of the electronic stimuli as the input.

15 . The non-transitory computer-readable storage medium of claim 14 , wherein the particular body part of the patient is at least one of a sub-part of at least one eye of the patient and a sub-part of the visual cortex of the patient.

16 . The non-transitory computer-readable storage medium of claim 15 , wherein the particular body part of the patient corresponds to at least one of a quantity of eyes and dimensions and/or locations of the eyes.

17 . The non-transitory computer-readable storage medium of claim 13 , further comprising:

identifying, by the device, a profile of the patient, the profile being an electronic medical record (EMR), the profile comprising information related to the status of the patient; and

analyzing, by the device, the profile, and determining symptoms of the medical condition of the patient, wherein the identified status of the patient corresponds to the determined symptoms of the medical condition.

18 . The non-transitory computer-readable storage medium of claim 13 , further comprising:

receiving, by the device, response data from a targeted portion of the visual cortex of the patient, the response data produced in response to the output of the electronic stimuli;

analyzing, by the device, the response data, and determining information related to the response of the patient; and

storing, by the device, the response data and the determined information in an electronic medical record (EMR) of the patient.

19 . A device comprising:

a processor configured to:

receive a request to provide a medical treatment to a patient, the medical treatment comprising instructions related to electronic stimuli to be output via a therapeutic medical device and delivered to a visual cortex of the patient, the treatment instructions further comprising information identifying at least one eye component of the therapeutic medical device to output the electronic stimuli;

identify a status of the patient, the status of the patient corresponding to a medical condition of the patient;

determine a type and value of the electronic stimuli based on the identified status of the patient;

automatically cause the therapeutic medical device to adjust a positioning of the at least one eye component based on the identified status and the determined type and value of the electronic stimuli, the adjusted positioning enabling the electronic stimuli to be output via the at least one eye component according to the type and value, the adjusted positioning further enabling the electronic stimuli to be directed to a particular body part of the patient; and

cause the adjusted therapeutic medical device to output the electronic stimuli provided in the medical treatment.

20 . The device of claim 19 , wherein the processor is further configured to:

determine, based on the status of the patient and the determined type and value of the electronic stimuli, the particular body part of the patient, wherein the determination of the particular body part is based on the device executing a machine learning (ML) algorithm with the status of the patient and the determined type and value of the electronic stimuli as the input.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 10, 2022
From: HANBURY, RICHARD
To: SANA HEALTH, INC.
Reel/Frame 059885/0365 →
Continuity (5)
Continuation In Part 17005047 · Aug 27, 2020
Continuation 16422592 · May 24, 2019
Continuation 15360808 · Nov 23, 2016
Provisional Application 62258965 · Nov 23, 2015
Related Publication 20220249803A1 · Aug 11, 2022
References Cited (113)
US 4172406A · Martinez · 1979 [cited by applicant]
US 4315502A · Gorges · 1982 [cited by applicant]
US 4892106A · Gleeson · 1990 [cited by applicant]
US 4966164A · Colsen et al. · 1990 [cited by applicant]
US 5343261A · Wilson · 1994 [cited by applicant]
US 5783909A · Hochstein · 1998 [cited by applicant]
US 6123661A · Fukushima et al. · 2000 [cited by applicant]
US 6409655B1 · Wilson et al. · 2002 [cited by applicant]
US 8562659B2 · Wells et al. · 2013 [cited by applicant]
US 8838247B2 · Hagedorn et al. · 2014 [cited by applicant]
US 8852073B2 · Genereux et al. · 2014 [cited by applicant]
US 8932199B2 · Berka et al. · 2015 [cited by applicant]
US D775260S · Gordon et al. · 2016 [cited by applicant]
US 9649469B2 · Hyde et al. · 2017 [cited by applicant]
US D805515S · Bowes et al. · 2017 [cited by applicant]
US D827701S · Nguyen et al. · 2018 [cited by applicant]
US 10328236B2 · Hanbury · 2019 [cited by applicant]
US 10383769B1 · Miller · 2019 [cited by applicant]
US 10449326B2 · Genereux et al. · 2019 [cited by applicant]
US 11141559B2 · Hanbury · 2021 [cited by applicant]
US 20020198577A1 · Jaillet · 2002 [cited by applicant]
US 20060106276A1 · Shealy et al. · 2006 [cited by applicant]
US 20060252979A1 · Vesely et al. · 2006 [cited by applicant]
US 20080269629A1 · Reiner · 2008 [cited by applicant]
US 20090156886A1 · Burgio · 2009 [cited by examiner]
US 20100056854A1 · Chang · 2010 [cited by applicant]
US 20100161010A1 · Thomas · 2010 [cited by applicant]
US 20100323335A1 · Lee · 2010 [cited by applicant]
US 20110075853A1 · Anderson · 2011 [cited by applicant]
US 20110213664A1 · Osterhout et al. · 2011 [cited by applicant]
US 20110257712A1 · Wells et al. · 2011 [cited by applicant]
US 20120095534A1 · Schlangen et al. · 2012 [cited by applicant]
US 20120211013A1 · Otis · 2012 [cited by applicant]
US 20130035734A1 · Soler Fernandez et al. · 2013 [cited by applicant]
US 20130225915A1 · Redfield et al. · 2013 [cited by applicant]
US 20130267759A1 · Jin · 2013 [cited by applicant]
US 20130303837A1 · Berka et al. · 2013 [cited by applicant]
US 20140336473A1 · Greco · 2014 [cited by applicant]
US 20150231395A1 · Saab · 2015 [cited by applicant]
US 20150268673A1 · Farzbod et al. · 2015 [cited by applicant]
US 20160228771A1 · Watson · 2016 [cited by applicant]
US 20170143935A1 · Hanbury · 2017 [cited by applicant]
US 20170189639A1 · Mastrianni · 2017 [cited by applicant]
US 20170252532A1 · Holsti et al. · 2017 [cited by applicant]
US 20170312476A1 · Woo · 2017 [cited by applicant]
US 20180184969A1 · Zhao et al. · 2018 [cited by applicant]
US 20180250494A1 · Hanbury · 2018 [cited by applicant]
US 20190030279A1 · Nowlin · 2019 [cited by applicant]
US 20190262576A1 · Mastrianni · 2019 [cited by applicant]
US 20190321584A1 · Hanbury · 2019 [cited by applicant]
US 20190388020A1 · Stauch et al. · 2019 [cited by applicant]
US 20200139112A1 · Aharonovitch · 2020 [cited by applicant]
US 20200268341A1 · Stroman · 2020 [cited by applicant]
US 20200368491A1 · Poltorak · 2020 [cited by applicant]
US 20200390999A1 · Hanbury · 2020 [cited by applicant]
US 20200391000A1 · Hanbury · 2020 [cited by applicant]
US 20210008332A1 · Jin et al. · 2021 [cited by applicant]
US 20220249803A1 · Hanbury · 2022 [cited by applicant]
US 20220265959A1 · Hanbury · 2022 [cited by applicant]
US 20220409849A1 · Hanbury · 2022 [cited by applicant]
AU 2016359154A1 · 2018 [cited by applicant]
CN 205814527U · 2016 [cited by applicant]
CN 104546285B · 2017 [cited by applicant]
CN 109152524A · 2019 [cited by applicant]
EA 035285B1 · 2020 [cited by applicant]
WO 2001064005A2 · 2001 [cited by applicant]
WO 2012117343A1 · 2012 [cited by applicant]
WO 2015028480A1 · 2015 [cited by applicant]
WO 2016140408A1 · 2016 [cited by applicant]
WO 2017091758A1 · 2017 [cited by applicant]
WO 2018160903A1 · 2018 [cited by applicant]
WO 2019060598A1 · 2019 [cited by applicant]
WO 2019226656A1 · 2019 [cited by applicant]
WO 2020172448A1 · 2020 [cited by applicant]
WO 2020219350A1 · 2020 [cited by applicant]
WO 2021007444A1 · 2021 [cited by applicant]
WO 2021236421A1 · 2021 [cited by applicant]
Aimee Corso, “Cognito Therapeutics Launched with Exclusive License to Promising Alzheimer's Research from the Massachusetts Institute of Technology”, Business Wire, Boston and San Francisco, https://www.businesswire.com… [cited by applicant]
Angus Chen, “An Hour of Light and Sound a Day Might Keep Alzheimer's at Bay”, Scientific American, https://www.scientificamerican.com/article/an-hour-of-light-and-sound-a-day-might-keep-alzheimers-at-bay/, Mar. 14, 2019… [cited by applicant]
Anne Trafton, “Ed Boyden receives 2018 Canada Gairdner International Award”, McGovern Institute, https://mcgovern.mit.edu/2018/03/27/ed-boyden-receives-2018-canada-gardner-international-award/, Mar. 27, 2018 (Mar. 27, 2… [cited by applicant]
Anthony J. Martorell, et al., “Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition”, Cell, https://www.cell.com/cell/fulltext/S0092-8674(19)30163-1, Mar. 14, 2019 (Mar. 14… [cited by applicant]
Chinnakkaruppan Adaikkan, et al., “Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection”, Neuron, https://linkinghub.elsevier.com/retrieve/pii/S0896627319303460, May 7, 2019 (May 7, 2019), 18 Pa… [cited by applicant]
Damian Garde, “‘Beyond amyloid’: A look at what's next in Alzheimer's research”, STAT, https://www.statnews.com/2017/08/18/beyond-amyloid-alzheimers-research/, Aug. 18, 2017 (Aug. 18, 2017), 5 Pages. [cited by applicant]
Dreamlight Zen; https://dreamlight.tech/products/dreamlight-zen; product description downloaded Aug. 3, 2021; 16 pages; Copyright 2021 Dreamlight. [cited by applicant]
Ed Yong, “Beating Alzheimer's With Brain Waves”, The Atlantic, https://www.theatlantic.com/science/archive/2016/12/beating-alzheimers-with-brain-waves/509846/, Dec. 7, 2016 (Dec. 7, 2016), 8 Pages. [cited by applicant]
Hannah Devlin, “Strobe lighting provides a flicker of hope in the fight against Alzheimer's”, The Guardian, https://www.theguardian.com/science/2016/dec/07/strobe-lighting-provides-a-flicker-of-hope-in-the-fight-against… [cited by applicant]
Hannah F. Iaccarino, et al., “Gamma frequency entrainment attenuates amyloid load and modifies microglia”, Nature, Journal, vol. 540, Dec. 7, 2016 (Dec. 7, 2016), pp. 230-235. [cited by applicant]
Helen Thomson, “How flashing lights and pink noise might banish Alzheimer's, improve memory and more”, Nature, https://www.nature.com/articles/d41586-018-02391-6, Feb. 28, 2018 (Feb. 28, 2018), 10 Pages. [cited by applicant]
Illumy by Sound Oasis; https://www.soundoasis.com/products/light-therapy/illumy-the-smart-sleep-mask/; Product description downloaded Aug. 2, 2021; 6 pages Copyright 2000-2021 AvivaHealth.com. [cited by applicant]
Jamie Ducharme, “The End of Alzheimer's?”, Boston, Magazine, https://www.bostonmagazine.com/health/2017/11/27/li-huei-tsai-alzheimers-treatment/, Nov. 27, 2017 (Nov. 27, 2017), 4 Pages. [cited by applicant]
Liviu Aron, et al., “Neural synchronization in Alzheimer's disease”, Nature, Journal, vol. 540, Dec. 7, 2016 (Dec. 7, 2016), pp. 207-208. [cited by applicant]
Lumos Smart Sleep Mask; https://lumos.tech/lumos-smart-sleep-mask/; Product description downloaded Aug. 3, 2021; 3 pages. [cited by applicant]
Meg Tirrell, “Could flashing light treat Alzheimer's? Fresh approaches to treating the disease”, CNBC, https://www.cnbc.com/2017/03/29/could-flashing-light-treat-alzheimers-fresh-approaches-to-treating-the-disease.html,… [cited by applicant]
Melissa Healy, “Flickering lights may illuminate a path to Alzheimer's treatment”, Los Angeles Times, Dec. 7, 2016 (Dec. 7, 2016), 3 Pages. [cited by applicant]
Molly Webster, et al., “Bringing Gamma Back”, WNYC Studios, https://www.wnycstudios.org/story/bringing-gammaback, Dec. 8, 2016 (Dec. 8, 2016), 3 Pages. [cited by applicant]
Nathan Hurst, “Could Flickering Lights Help Treat Alzheimer's?”, Smithsonian, https://www.smithsonianmag.com/innovation/could-flickering-lights-help-treat-alzheimers-180961762/, Jan. 11, 2017 (Jan. 11, 2017), 2 Pages. [cited by applicant]
Nicole Wetsman, “Flickering light seems to help mice with Alzheimer's-like symptoms”, Popular Science, https://www.popsci.com/flickering-light-genes-alzheimers, May 7, 2019 (May 7, 2019), 2 Pages. [cited by applicant]
NSTC, “First Friday Biosciences: Nov. 3 in Woburn”, https://www.nstc.org/previous-events/first-friday-biosciencesnov-3-in-woburn/, Nov. 3, 2017 (Nov. 3, 2017), 8 Pages. [cited by applicant]
Pam Belluck, “A Possible Alzheimer's Treatment With Clicks and Flashes? It Worked on Mice”, New York Times, https://www.nytimes.com/2019/03/14/health/alzheimers-memory.html, Mar. 14, 2019 (Mar. 14, 2019), 5 Pages. [cited by applicant]
Pam Belluck, “Could simply listening to this sound help cure Alzheimer's disease? MIT researchers are Investigating”, Boston Globe, https://www.bostonglobe.com/news/science/2019/03/14/could-simply-listening-thissound-he… [cited by applicant]
Remee Lucid Dreaming Mask; http://sleepwithremee.com/; Product description downloaded Aug. 3, 2021; 10 pages; Copyright 2018 Bitbanger LLC. [cited by applicant]
Robert Weisman, “MIT team uses LEDs to attack Alzheimer's”, Boston Globe, https://www.bostonglobe.com/business/2016/12/07/led-technology-from-mit-used-startup-working-alzheimer-treatment/Kbdjp9WvfoPLfC1bNhvGOI/story.htm… [cited by applicant]
The Picower Institute, “Tsai earns Hans Wigzell Research Foundation Science Prize”, https://picower.mit.edu/news/tsai-earns-hans-wigzell-research-foundation-science-prize, Jan. 23, 2019 (Jan. 23, 2019), 3 Pages. [cited by applicant]
European Patent Office, Extended European Search Report dated Nov. 27, 2020 for European Patent Application No. 18761087.8, 9 pages. [cited by applicant]
European Patent Office, Supplementary European Search Report mailed Jun. 5, 2019 for European Patent Application No. 16869299.4, 8 pages. [cited by applicant]
Intellectual Property India, Examination Report for Application No. 201837022885, dated May 6, 2021; 7 pages. [cited by applicant]
International Searching Authority, International Search Report and Written Opinion for PCT/US2016/063651, mailed Feb. 3, 2017; 13 pages. [cited by applicant]
International Searching Authority, International Search Report and Written Opinion for PCT/US2019/033322, mailed Aug. 2, 2019; 11 pages. [cited by applicant]
International Searching Authority, International Search Report and Written Opinion for PCT/US2020/019091, mailed May 6, 2020; 13 pages. [cited by applicant]
International Searching Authority, International Search Report and Written Opinion for PCT/US2020/41423, mailed Oct. 9, 2020; 9 pages. [cited by applicant]
International Searching Authority, International Search Report and Written Opinion for PCT/US2021/032260, mailed Aug. 31, 2021; 9 pages. [cited by applicant]
International Searching Authority, International Search Report and Written Opinion for PCT/US2018/020547, mailed May 7, 2018; 10 pages. [cited by applicant]
Canadian Intellectual Property Office, Office Action mailed Dec. 7, 2022 for Canadian Patent Application No. 3029198, 4 pages. [cited by applicant]