IP Library Granted Patent US 11,884,541
Granted Patent B2
US 11,884,541 · App. 17/727,489 · Granted Jan 30, 2024

Conversion of nitrogen dioxide (NO

Inventors: David H. Fine (Cocoa Beach, FL); Gregory Vasquez (Cocoa, FL); David P. Rounbehler (Lexington, MA)
Assignee: VERO BIOTECH INC.
C01B21/32A61D7/04A61K33/00A61M16/009A61M16/0051A61M16/0057A61M16/104A61M16/1075A61M16/12A61M16/16C01B21/24G01N27/416A61M16/107A61M16/1055A61M2016/102A61M2202/0275Y10T436/179228
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Quick Facts
Patent No.
US 11,884,541
App. No.
17/727,489
Granted
Jan 30, 2024
Kind
B2
Abstract

Various systems, devices, NO 2 absorbents, NO 2 scavengers and NO 2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.

Claims (8)

1. An apparatus for delivering nitric oxide to a patient, comprising:

a gas source including nitrogen dioxide;

a cartridge coupled to the gas source configured to convert nitrogen dioxide from the gas source into nitric oxide;

a source of air downstream of the cartridge and configured to dilute a flow of gas that exited the cartridge; and

at least one recuperator configured to further convert nitrogen dioxide into nitric oxide.

2. The apparatus of claim 1 , wherein the at least one recuperator is further configured to provide a bacterial and viral filtration of the gas.

3. The apparatus of claim 1 , further comprising a gas analyzer disposed downstream of the source of air, the gas analyzer configured to measure the concentration of nitric oxide and nitrogen dioxide in the flow of gas after dilution with the source of air.

4. The apparatus of claim 3 , wherein the gas analyzer is coupled to the at least one recuperator.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Mar 18, 2026
From: HORIZON TECHNOLOGY FINANCE CORPORATION
To: VERO BIOTECH INC.
Reel/Frame 075308/0198 →
SECURITY INTEREST Recorded Mar 16, 2026
From: VERO BIOTECH INC.
To: SYMBIOTIC CAPITAL AGENCY LLC, AS COLLATERAL AGENT
Reel/Frame 075117/0935 →
SECURITY INTEREST Recorded Jan 3, 2024
From: VERO BIOTECH INC.
To: HORIZON TECHNOLOGY FINANCE CORPORATION
Reel/Frame 066187/0865 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 27, 2022
From: FINE, DAVID; VASQUEZ, GREGORY; ROUNBEHLER, DAVID P.
To: GENO LLC
Reel/Frame 060324/0637 →
CHANGE OF NAME Recorded Jun 27, 2022
From: GENO LLC
To: VERO BIOTECH LLC
Reel/Frame 060445/0751 →
CHANGE OF NAME Recorded Jun 27, 2022
From: VERO BIOTECH LLC
To: VERO BIOTECH INC.
Reel/Frame 060445/0764 →
Continuity (10)
Division 16512021 · Jul 15, 2019
Continuation 16140497 · Sep 24, 2018
Continuation 15645197 · Jul 10, 2017
Continuation 14294070 · Jun 2, 2014
Continuation 14107535 · Dec 16, 2013
Continuation 13480376 · May 24, 2012
Division 13072466 · Mar 25, 2011
Division 12361274 · Jan 28, 2009
Provisional Application 61024178 · Jan 28, 2008
Related Publication 20230077727A1 · Mar 16, 2023