IP Library › Granted Patent US 12,268,392
Granted Patent B2
US 12,268,392 · App. 17/735,291 · Granted Apr 8, 2025

Anastomosis devices

Inventors: Daniel H. Todd (North East, MD); Sakthi Sambandam (Elkton, MD)
Assignee: W. L. Gore & Associates, Inc.
A61B17/1114A61B17/0057A61B17/11A61F2/06A61F2/90A61B17/064A61B2017/0641A61B17/08A61B17/083A61B2017/1103A61B2017/1107A61B2017/1132A61B2017/1135A61B2017/1139A61F2002/077
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Quick Facts
Patent No.
US 12,268,392
App. No.
17/735,291
Filed
May 3, 2022
Granted
Apr 8, 2025
Kind
B2
Art Unit
3771
USPC
606/151
Abstract

Implantable medical devices for connecting tissue layers, such as for connecting a gallbladder and a portion of a gastrointestinal tract to create an anastomosis, include a tubular structure having a plurality of apposition portions, a central region, and a covering material. The devices are endoscopically deployable and may include open cells or undulating edges that facilitate a secure connection between the tissue structures.

Claims (39)

1. An implantable medical device comprising:

a tubular structure comprising at least one elongate member forming a framework of interconnected struts, the tubular structure including:

a central portion defining a longitudinal axis and including a plurality of central portion cells defined by the at least one elongate member, wherein the central portion cells are open to longitudinally-adjacent central portion cells and are closed to circumferentially-adjacent central portion cells;

a first apposition portion at a first end of the central portion, the first apposition portion comprising a plurality of first flange cells defined by the at least one elongate member;

a second apposition portion at a second end of the central portion, the second apposition portion comprising a plurality of second flange cells defined by the at least one elongate member, wherein at least some of the second flange cells are closed at a first end by an undulating portion of the at least one elongate member and opened at a second end to the central portion; and

a covering material configured to be at least partially disposed on at least one of the central portion, the first apposition portion, and the second apposition portion.

2. The device of claim 1 , wherein the at least one elongate member forms a first pattern extending longitudinally along the central portion, a first flange cell of the plurality of first flange cells, a second pattern extending longitudinally along the central portion, the second pattern opposing the first pattern, a second flange cell of the plurality of second flange cells.

3. The device of claim 2 , wherein the at least one elongate member comprises a single elongate member that forms the central portion, the first apposition portion, and the second apposition portion.

4. The device of claim 1 , wherein the at least one elongate member forms a pattern so as to first define a first flange cell of the plurality of first flange cells, the elongate member second traverses the central portion, the elongate member third defines a second flange cell of the plurality of second flange cells, the elongate member fourth traverses the central portion, and thereafter the elongate member repeats the pattern to form additional flange cells of the first and second plurality of flange cells while traversing the central portion in between.

5. The device of claim 4 , wherein each successive flange cell of the first and second plurality of flange cells is out of phase with directly preceding flange cells of the first and second plurality of flange cells.

6. The device of claim 1 , wherein each first flange cell of the plurality of first flange cells is open to a respective central portion cell of the plurality of central portion cells, and wherein each second flange cell of the plurality of second flange cells is open to another respective central portion cell of the plurality of central portion cells.

7. The device of claim 1 , wherein each of the plurality of second flange cells is open to one or more of the central portion cells of the plurality of central portion cells.

8. The device of claim 1 , wherein the undulating portion is sinusoidal.

9. The device of claim 1 , wherein each of the first and second apposition portions comprises circumferential rings that undulate substantially sinusoidally along edges thereof.

10. The device of claim 1 , wherein the central portion cells are open to a gap between struts of at least one of the first and second apposition portions.

11. The device of claim 1 , wherein the central portion comprises a plurality of body struts each comprising a plurality of longitudinally-extending portions interconnected with a plurality of angled portions that combine to define the plurality of central portion cells without interconnecting adjacent body struts across the central portion cells along the length of the body struts.

12. The device of claim 1 , wherein the covering material inhibits tissue ingrowth into the covering material.

13. The device of claim 1 , wherein at least a portion of the covering material comprises a microporous structure to provide a tissue ingrowth scaffold.

14. The device of claim 1 , wherein the covering material is configured to release a pharmacological agent to promote tissue ingrowth.

15. The device of claim 14 , wherein the pharmacological agent is covalently attached to the covering material.

16. The device of claim 14 , wherein the covering material is impregnated with the pharmacological agent.

17. The device of claim 1 , wherein the framework of interconnected struts is compressible to extend substantially parallel to the central portion.

18. The device of claim 1 , wherein the framework of interconnected struts is compressible into a low-profile configuration for containment within a catheter for delivery and is also self-expandable to an operative size when deployed from the catheter.

19. An implantable medical device comprising:

a tubular structure comprising at least one elongate member forming a framework of interconnected struts, the tubular structure defining:

a central portion comprising a plurality of body cells defined by the at least one elongate member, wherein the central portion comprise a plurality of body struts each having a plurality of axially-extending portions interconnected with a plurality of angled portions that combine to define the plurality of body cells without interconnecting adjacent body struts across the body cells along the length of the body struts;

a first apposition portion at a first end of the central portion having a plurality of first flange cells defined by the at least one elongate member such that the plurality of first flange cells are open to the central portion; and

a second apposition portion at a second end of the central portion comprising a plurality of second flange cells defined by the at least one elongate member such that the plurality of second flange cells are open to the central portion,

wherein the framework of interconnected struts is compressible into a low-profile configuration for delivery and is also self-expandable to an operative size.

20. The device of claim 19 , wherein the at least one elongate member is formed such that the at least one elongate member forms a first pattern traversing the central portion along a longitudinal axis, the elongate member defines a first flange cell of the plurality of first flange cells, the elongate member traverses the central portion along the longitudinal axis in a second pattern opposing said first pattern, and the elongate member defines a second flange cell of the plurality of second flange cells.

21. The device of claim 19 , wherein the at least one elongate member is formed in a pattern so as to first define a first flange cell of the plurality of first flange cells, the elongate member second traverses the central portion, the elongate member third defines a second flange cell of the plurality of second flange cells, the elongate member fourth traverses the central portion, and thereafter the elongate member repeats the pattern to form additional flange cells of the first and second plurality of flange cells while traversing the central portion in between.

22. The device of claim 19 , wherein the body cells are open to longitudinally-adjacent body cells and are closed to circumferentially-adjacent body cells, wherein each of the plurality of first and second flange cells is open to one or more of the plurality of body cells.

23. The device of claim 19 , wherein each of the first and second apposition portions comprises circumferential rings that undulate substantially sinusoidally along edges thereof.

24. An implantable medical device comprising:

a tubular structure comprising at least one elongate member forming a framework of interconnected struts, the tubular structure defining:

a central portion having a plurality of body cells defined by the at least one elongate member;

a first apposition portion at a first end of the central portion having a plurality of first flange cells defined by the at least one elongate member; and

a second apposition portion at a second end of the central portion having a plurality of second flange cells defined by the at least one elongate member, wherein the framework of interconnected struts is compressible to extend substantially parallel to the central portion, wherein the at least one elongate member is formed such that the at least one elongate member forms a first pattern traversing the central portion along a longitudinal axis, the elongate member defines a first flange cell of the first plurality of flange cells, the elongate member traverses the central portion along the longitudinal axis in a second pattern opposing said first pattern, and the elongate member defines a second flange cell of the second plurality of flange cells,

wherein each successive flange cell of the first and second plurality of flange cells is out of phase with directly preceding flange cells of the first and second plurality of flange cells, wherein the body cells are open to longitudinally-adjacent body cells and are closed to circumferentially-adjacent body cells, and wherein each of the plurality of first flange cells is open to the central portion and each of the plurality of second flange cells is open to the central portion.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 7, 2025
From: TODD, DANIEL H.; SAMBANDAM, SAKTHI
To: W. L. GORE & ASSOCIATES, INC.
Reel/Frame 070441/0725 →
Continuity (4)
Continuation 15970648 · May 3, 2018
Continuation 14700505 · Apr 30, 2015
Provisional Application 61987954 · May 2, 2014
Related Publication 20220257252A1 · Aug 18, 2022
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