IP Library › Granted Patent US 12,478,376
Granted Patent B2
US 12,478,376 · App. 18/630,075 · Granted Nov 25, 2025

Anastomosis devices

Inventors: Michael J. Houghton (Newark, DE); Sakthi Sambandam (Elkton, MD); Clifford P. Warner (West Chester, PA)
Assignee: W. L. Gore & Associates, Inc.
A61B17/1114A61B17/0057A61B17/11A61F2/06A61F2/90A61B17/064A61B2017/0641A61B17/08A61B17/083A61B2017/1103A61B2017/1107A61B2017/1132A61B2017/1135A61B2017/1139A61F2002/077
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Quick Facts
Patent No.
US 12,478,376
App. No.
18/630,075
Granted
Nov 25, 2025
Kind
B2
Abstract

Implantable medical devices for connecting tissue layers, such as for connecting a gallbladder and a portion of a gastrointestinal tract to create an anastomosis, include a tubular structure having a plurality of apposition portions, a central region, and a covering material. The methods of using the devices include endoscopic deployment, and the devices may include self-expanding frameworks that facilitate a secure connection between the tissue structures.

Claims (38)

1 . A medical device comprising:

a frame comprising an elongate member defining:

a first apposition portion comprising one or more first flange members configured to contact a first tissue surface and to provide an apposition force against said first tissue surface;

a second apposition portion comprising one or more second flange members configured to contact a second tissue surface and to provide an apposition force against said second tissue surface; and

a central portion having a first end and a second end, said central portion defining a longitudinal axis, said central portion being disposed between and interconnecting said first apposition portion and said second apposition portion, the central portion including axial adjustment members and the axial adjustment members interconnected by a single cell or by two or more cells,

wherein at least one of said one or more first flange members and at least one of said second flange members comprises a radius portion extending from the central portion and a descending portion that extends from the radius portion and longitudinally toward said central portion,

wherein at least one of said radius portions of said one or more first flange members extends longitudinally beyond said first end, and

wherein at least one of said radius portions of said one or more second flange members extends longitudinally beyond said second end.

2 . The medical device of claim 1 , wherein at least one of said one or more first flange members or at least one of said one or more second flange members further comprise a horizontal portion extending from said descending portion.

3 . The medical device of claim 1 , wherein each of said one or more first flange members and each of said second flange members comprises a radius portion and a descending portion that extends longitudinally toward said central portion.

4 . The medical device of claim 1 , wherein said radius portions extend from said first end or said second end of said central portion.

5 . The medical device of claim 1 , wherein said descending portion is a linearly descending portion.

6 . The medical device of claim 1 , wherein the central portion defines a lumen extending between said first end and said second end.

7 . The medical device of claim 1 , wherein the central portion is configured to longitudinally extend and retract to maintain contact, over a range of tissue thicknesses, of the first and second apposition portions with the first and second tissue surfaces respectively.

8 . The medical device of claim 1 , wherein the radius portion includes a first radius portion and a second radius portion, wherein the first radius portion curves in a first direction and the second radius portion curves in a second direction opposite from the first direction.

9 . The medical device of claim 1 , wherein the one or more first flange members includes a flange end that longitudinally overlaps with the central portion.

10 . An anastomosis device comprising:

a frame comprising an elongate member defining:

a first apposition portion comprising one or more first flange members configured to contact a first tissue surface and to provide an apposition force against said first tissue surface;

a second apposition portion comprising one or more second flange members configured to contact a second tissue surface and to provide an apposition force against said second tissue surface; and

a central portion having a first end and a second end, said central portion comprised of a framework of one or more elongate elements and defining a longitudinal axis, said central portion being disposed between and interconnecting said first apposition portion and said second apposition portion, the central portion including one or more axial adjustment members and one or more cells interconnecting the one or more axial adjustment members,

wherein the one or more axial adjustment members extend along the longitudinal axis of the central portion and are configured to allow the central portion to elastically

extend or contract the central portion along the longitudinal axis, and wherein the one or more first flange members includes a flange end that longitudinally overlaps with the central portion.

11 . The device of claim 10 , wherein the one or more cells expand in the circumferential direction and collapse in the longitudinal direction, during radial expansion of the central portion.

12 . The device of claim 10 , wherein the one or more cells have a diamond-like shape.

13 . The device of claim 10 , wherein the one or more axial adjustment members are interconnected by a single cell or by two or more cells.

14 . The device of claim 10 , further comprising a covering material on at least a portion of said frame.

15 . The device of claim 14 , wherein the covering material comprises a fluoropolymer.

16 . The device of claim 14 , wherein the covering material is fluid impermeable.

17 . The device of claim 14 , wherein the covering material can accommodate changes in length and/or diameter of the device.

18 . The device of claim 10 , wherein at least one of said one or more first flange members and at least one of said second flange members comprises a radius portion and a descending portion that extends longitudinally toward said central portion,

wherein at least one of said radius portions of said one or more first flange members extends longitudinally beyond said first end,

wherein at least one of said radius portions of said one or more second flange members extends longitudinally beyond said second end, and

wherein at least one said first apposition members is configured differently than one or more others of said first apposition members.

19 . The device of claim 18 , wherein at least one of said one or more first flange members or at least one of said one or more second flange members further comprises a horizontal portion extending from said descending portion.

20 . The device of claim 18 , wherein each of said one or more first flange members and each of said second flange members comprises a radius portion and a descending portion that extends longitudinally toward said central portion.

21 . The device of claim 20 , wherein said radius portions extend from said first end or said second end of said central portion.

22 . The device of claim 20 , wherein said descending portion is a linearly descending portion.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 23, 2024
From: HOUGHTON, MICHAEL J.; SAMBANDAM, SAKTHI; WARNER, CLIFFORD P.
To: W. L. GORE & ASSOCIATES, INC.
Reel/Frame 069665/0155 →
Continuity (4)
Continuation 16741379 · Jan 13, 2020
Continuation 14700427 · Apr 30, 2015
Provisional Application 61987954 · May 2, 2014
Related Publication 20240252175A1 · Aug 1, 2024
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