IP Library › Granted Patent US 12,478,362
Granted Patent B2
US 12,478,362 · App. 18/208,590 · Granted Nov 25, 2025

Occluder and anastomosis devices

Inventors: Matthew A. Johnson (Bear, DE); Nathan K. Mooney (Elkton, MD); Christopher S. Michalak (Elkton, MD)
Assignee: W. L. Gore & Associates, Inc.
A61B17/0057A61B17/11A61B17/12022A61B17/12031A61B17/12099A61B90/39A61B2017/00592A61B2017/00597A61B2017/00615A61B2017/00623A61B2017/00632A61B2017/00676A61B2017/00818A61B2017/00867A61B2017/1103A61B17/1114A61B2017/1139A61B2017/1205A61B17/12145A61B2090/3966
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Quick Facts
Patent No.
US 12,478,362
App. No.
18/208,590
Granted
Nov 25, 2025
Kind
B2
Abstract

An implantable medical device for sealing and repairing defects in a body tissue or for creating an anastomosis includes a frame and a covering material. In some embodiments, the frame includes a single continuously wound wire that defines an apposition portion, a defect-occupying portion, and a sealing portion. In some embodiments, the tissue-sealing and anastomosis devices provided herein are well-suited for use in the GI tract including the small bowel and colon. In some embodiments, a two-part frame construct facilitates independent tailoring of apposition forces and radial forces exerted on tissues by the two-part frame.

Claims (28)

1 . A medical device for sealing a defect or structure in tissue, the device comprising:

a frame comprising a single elongate member, the single elongate member defining:

a supporting portion configured to conform to a geometry of a first tissue surface and to provide an apposition force against the first tissue surface, wherein the supporting portion comprises a plurality of first features;

an occluding portion configured to conform to a geometry of a second tissue surface and to provide an apposition force against the second tissue surface, wherein the occluding portion comprises a plurality of second features, wherein the second features comprise wire petals, and wherein each of the wire petals is configured to be separated from adjacent wire petals such that each of the wire petals are not in contact with the adjacent wire petals and define closed loops; and

a defect-occupying portion disposed between the supporting portion and the occluding portion, the defect-occupying portion configured to not provide substantial apposition force against tissue around an aperture of the defect; and

a sealing material attached to at least a portion of the occluding portion, the sealing material configured to inhibit material flow through the aperture,

wherein the single elongate member is wound in a pattern comprising: 1) the single elongate member defines one of the first features, 2) the single elongate member traverses the defect-occupying portion, 3) the single elongate member defines one of the second features, 4) the single elongate member traverses the defect-occupying portion, and thereafter the single elongate member repeats the pattern.

2 . The device of claim 1 , wherein the first features comprise elongate wire loops, and wherein each of the elongate wire loops is configured to bear a load associated with the first tissue surface without imparting a substantial force to any other elongate wire loops of the supporting portion.

3 . The device of claim 1 , wherein each of the wire petals is configured to move independently of any other petal of the occluding portion.

4 . The device of claim 1 , wherein the sealing material is configured to inhibit tissue ingrowth and endothelialization into the sealing material.

5 . The device of claim 1 , further comprising one or more radiopaque markers disposed on the medical device.

6 . The device of claim 1 , wherein the frame further comprises one or more tissue anchorage features.

7 . The device of claim 1 , wherein the occluding portion includes eight petals.

8 . The device of claim 1 , wherein the first features of the supporting portion comprise wire petals, and the wire petals of the occluding portion are non-parallel with the wire petals of the supporting portion.

9 . A medical device for sealing a defect or structure in tissue, the medical device comprising:

a wire frame that includes a single wound wire, the single wound wire forming:

a sealing member, wherein the sealing member comprises one or more petals and wherein each petal of the one or more petals is configured to be separated from adjacent wire petals such that each of the wire petals are not in contact with the adjacent wire petals and define closed loops;

an apposition member; and

a defect-occupying portion disposed between the sealing member and the apposition member; and

a covering material disposed on at least a portion of the sealing member,

wherein the single wound wire is wound in a pattern comprising: 1) the single wound wire defines a petal of the one or more petals, 2) the single wound wire traverses the defect-occupying portion, 3) the single wound wire defines a second feature of the apposition member, 4) the single wound wire traverses the defect-occupying portion, and thereafter the single wound wire repeats the pattern.

10 . The device of claim 9 , wherein each petal of the one or more petals is configured to move independently of any other petal of the sealing member.

11 . The device of claim 9 , wherein each petal of the one or more petals is configured to at least partially overlap adjacent petals.

12 . The device of claim 9 , wherein the sealing member comprises one or more portions of the single wound wire that, when combined, define an outer generally circular periphery of the sealing member.

13 . The device of claim 9 , wherein the apposition member comprises one or more wire loops.

14 . The device of claim 13 , wherein each wire loop of the one or more wire loops is configured to move independently of any other wire loop of the one or more wire loops.

15 . The device of claim 13 , wherein the apposition member is configured to conform to a geometry of a first tissue surface and to provide an apposition force against the first tissue surface, and wherein each wire loop of the one or more wire loops is configured to bear a load associated with the first tissue surface without imparting a substantial force to any other wire loop of the one or more wire loops.

16 . The device of claim 9 , wherein the sealing member comprises eight petals.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2023
From: JOHNSON, MATTHEW A.; MOONEY, NATHAN K.; MICHALAK, CHRISTOPHER S.
To: W. L. GORE & ASSOCIATES, INC.
Reel/Frame 064926/0465 →
Continuity (3)
Division 14701440 · Apr 30, 2015
Provisional Application 61987802 · May 2, 2014
Related Publication 20230320714A1 · Oct 12, 2023
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