Granted Patent
B2
US 12,605,537 · App. 18/108,414 · Granted Apr 21, 2026
Implantable medical device for use with or having recording electrode
Inventors:
Daniel J. Abrams (Denver, CO); Matias Maturana (Melbourne, AU); Ross Thomas (Melbourne, AU); Christopher Smith (Melbourne, AU)
Assignee:
Biogen MA Inc.
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Abstract
A burr hole device is configured to receive a catheter and a cable of a sheath. The sheath is configured to receive a portion of the catheter and has an electrode. When the catheter and sheath are implanted with the burr hole device, the catheter and electrode of the sheath are implanted in a brain. Systems and apparatuses may include the burr hole device and/or a cranial port device, the catheter, and the sheath.
Claims (24)
1 . A burr hole device comprising:
a body comprising a flange portion adapted to be disposed on a surface of a skull adjacent to a burr hole in the skull of a subject, the flange portion having a first surface and a second surface opposite the first surface;
a lower portion configured to be placed within the burr hole, the lower portion having a tubular portion and a third surface disposed along a bottom surface of the tubular portion, the lower portion configured to be placed within the burr hole; and
a lumen extending from the first surface to the third surface, wherein the lumen is configured to receive a catheter configured to allow fluid to flow to or from a brain of the subject,
wherein the flange portion defines a top groove along the first surface, the top groove extending from the lumen towards a lateral edge of the flange portion to receive the catheter,
wherein the body further defines a cable groove comprising a first groove portion extending from a lateral edge of the second surface towards the lumen, a second groove portion along an outer surface of the tubular portion and a third groove portion extending from a lateral edge of the third surface towards the lumen, and
wherein the cable groove is configured to receive a cable.
2 . The burr hole device of claim 1 , wherein the lower portion of the body is configured to have a clearance of 1 millimeter or less when adapted to be disposed in the burr hole.
3 . The burr hole device of claim 1 , wherein the lower portion of the body has an outer diametric dimension from 10 millimeters to 20 millimeters.
4 . The burr hole device of claim 1 , wherein the upper flange portion of the body has an outer diametric dimension from 15 millimeters to 30 millimeters.
5 . An assembly comprising:
the burr hole device of claim 1 ; and
a sheath disposed adjacent to the burr hole device comprising (i) a sheath body defining a sheath lumen configured to receive the catheter, (ii) a recording electrode disposed on the sheath body, (iii) the cable, and (iv) a conductor electrically coupled to the recording electrode and extending in the cable.
6 . A method comprising:
providing the assembly of claim 5 ;
disposing the burr hole device in the burr hole of the subject;
inserting the catheter through the top groove of the flange portion;
inserting the catheter through the lumen of the burr hole device;
inserting the catheter through the sheath lumen;
implanting a distal end of the catheter in the brain of the subject;
implanting the recording electrode of the sheath beneath the skull of the subject;
inserting the cable of the sheath in the first, second and third groove portions of the cable groove.
7 . The method of claim 6 , wherein implanting the recording electrode of the sheath beneath the skull of the subject further comprises implanting the recording electrode in the brain of the subject.
8 . The method of claim 6 , wherein implanting a distal end of the catheter in the brain of the subject comprises implanting the distal end of the catheter in a cerebral ventricle.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Nov 1, 2024
From: CEREBRAL THERAPEUTICS, INC.
To: BIOGEN MA INC.
Reel/Frame 069104/0201 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 22, 2023
From: ABRAMS, DANIEL J.; MATURANA, MATIAS; THOMAS, ROSS; SMITH, CHRISTOPHER
To: CEREBRAL THERAPEUTICS, INC.
Reel/Frame 062762/0621 →
Continuity (2)
Provisional Application
63310288
· Feb 15, 2022
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