Granted Patent B2

US 12,635,685 · App. 18/306,084 · Granted May 26, 2026

Inventors: Jared Alden Judson (Medford, MA); Lisa Maria Anderson (Cambridge, MA); William Edelman (Sharon, MA)

Assignee: Paragonix Technologies, Inc.

A01N1/142A01N1/143A01N1/148

Abstract

Claims (22)

1 . A method for storage of an organ, the method comprising:

providing an organ container comprising:

an expandable accumulator comprising an expandable inner volume; and

an organ adapter comprising a lumen in fluid communication with the expandable inner volume and configured to be coupled to a lumen of an organ to form a closed air system between the expandable inner volume and the lumen of the organ,

wherein the expandable accumulator has an expansion resistance that is less than the expansion resistance of the lumen of the organ, and

coupling the lumen of an organ to the organ adapter.

2 . The method of claim 1 , wherein the organ is one or more lungs and the lumen of the organ is selected from the group consisting of a trachea or bronchus of the one or more lungs.

3 . The method of claim 2 , wherein the organ container further comprises a raised central portion configured to be placed against an organ within the organ container, the method further comprising disposing the one or more lungs against the raised central portion.

4 . The method of claim 1 , wherein the organ container further comprises an inlet comprising a lumen and coupled to the expandable accumulator by an inlet valve such that the lumen of the inlet is in fluid communication with the lumen of the organ when the inlet valve is opened and the closed air system between the expandable inner volume and the lumen of the organ is formed when the inlet valve is closed, the method further comprising;

coupling a gas source to the inlet;

opening the inlet valve;

filling the lumen of the organ with gas from the gas source to a desired pressure;

closing the inlet valve;

removing the gas source from the inlet; and

closing the organ container with the organ disposed therein.

5 . The method of claim 1 , wherein the expansion resistance of the expandable accumulator is adjustable.

6 . The method of claim 1 , wherein the expandable accumulator comprises a bellows.

7 . The method of claim 1 , wherein the expandable accumulator comprises a weight that provides the expansion resistance of the expandable accumulator.

8 . The method of claim 1 , wherein the expandable accumulator comprises a spring that provides the expansion resistance of the expandable accumulator.

9 . The method of claim 1 , wherein the expandable accumulator comprises an expandable bladder comprising an elastic material wherein the elastic material provides the expansion resistance of the expandable accumulator.

10 . The method of claim 1 , wherein the expandable accumulator comprises a rolling diaphragm.

11 . The method of claim 1 , wherein the expandable accumulator has an adjustable volume, the method further comprising adjusting the volume of the expandable accumulator based on ambient pressure when coupling the lumen of the organ to the organ adapter.

Assignments (1)

Continuity (6)

References Cited (400)