Granted Patent
B2
US 12,342,826 · App. 18/513,577 · Granted Jul 1, 2025
Method of identifying a biologically-active composition from a biofilm
Inventors:
Eva A. Berkes (Sarasota, FL); Nicholas T. Monsul (Sarasota, FL); Frederick T. Boehm (Sarasota, FL)
Assignee:
QUORUM INNOVATIONS, LLC
A01N63/20A61K8/34A61K8/67A61K8/981A61K8/988A61K8/99A61K9/0014A61K9/0043A61K9/0046A61K9/0048A61K9/007A61K35/644A61K35/74A61K35/744A61K35/747A61K39/092A61K45/06A61K47/10A61Q11/00A61Q17/005A61Q19/007A61Q19/10C12N1/20C12Q1/04C12Q1/18A61K36/61A61K39/39A61K2300/00A61K2800/78A61K2800/782G01N2333/315G01N2333/335Y02A50/30
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Abstract
The subject invention provides materials and methods that effectively support innate immunity and/or disperse pathogenic biofilms using readily available, nontoxic, natural substances, while supporting restoration of normal microbiotic homeostasis. In one embodiment, the subject invention provides anti-biofilm compositions comprising one or more probiotic organisms, anti-microbial honey, and other ingredients such as prebiotic compounds, other hive products, green tea derivatives, other plant derivatives, and vitamin D3.
Claims (4)
1. A method for the control of biofilm on an inanimate surface wherein said method reduces biofilm attachment; inhibits biofilm growth; disrupts a biofilm matrix; prevents, inhibits, and/or disrupts secretion and/or release of biofilm extracellular factors; and/or prevents, inhibits, and/or disrupts quorum-sensing mechanisms of a biofilm; wherein said method comprises applying to the inanimate surface a composition comprising microbial biofilm cellular mass, exopolysaccharides, and a biologically-active agent produced by the microbial biofilm.
2. The method, according to claim 1 , wherein the microbe is selected from the group consisting of Bacteroides, Bifidobacterium , and Lactobacillus.
3. The method, according to claim 2 , wherein the microbe is a Lactobacillus.
4. The method, according to claim 1 , wherein the biofilm cellular mass is non-viable.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 13, 2025
From: QUORUM INNOVATIONS, LLC
To: QUORUM INNOVATIONS, INC.
Reel/Frame 072547/0227 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 4, 2023
From: BERKES, EVA A.; MONSUL, NICHOLAS T.; BOEHM, FREDERICK T.
To: QUORUM INNOVATIONS, LLC
Reel/Frame 065745/0514 →
Continuity (12)
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