Granted Patent B2

US 12,599,397 · App. 18/562,038 · Granted Apr 14, 2026

Inventors: Aadel Al-Jadda (San Carlos, CA); Tom Saul (Portland, OR); Kevin Muller (San Carlos, CA); Amr Salahieh (Saratoga, CA)

Assignee: Shifamed Holdings, LLC

A61B17/32037A61B17/00234A61B17/22A61B2017/00238A61B2017/00292A61B2017/22079A61B2217/005A61B2217/007

Abstract

Claims (24)

1 . A thrombus removal system, comprising:

an elongated catheter device including:

a distal portion configured to be positioned within a blood vessel of a patient, the distal portion comprising an inner wall forming an aspiration lumen, and an outer wall, and a fluid lumen formed in a space between the inner wall and the outer wall;

a manifold formed near a distal end of the fluid lumen and the aspiration lumen, the manifold including a first fluid port and a second fluid port formed therein and surrounded by the manifold, the first fluid port having a first axis, the second fluid port having a second axis, wherein the first axis intersects with the second axis at a fluid intersection within the distal portion, the first fluid port and the second fluid port being configured to direct respective fluid streams along the first axis and the second axis that collide at the fluid intersection within the distal portion;

a proximal portion configured to be positioned external to the patient, the aspiration lumen extending from the distal portion to the proximal portion;

an aspiration mechanism positioned external to the patient and fluidly coupled with the aspiration lumen, the aspiration mechanism configured to reduce a pressure at the distal portion (a) to engage a thrombus therewith and/or (b) to draw the thrombus and/or thrombus fragments proximally; and

a fluid delivery mechanism configured to supply fluid through the fluid lumen.

2 . The system of claim 1 wherein the inner wall and the outer wall are concentrically arranged such that the fluid lumen is generally annular in cross-section.

3 . The system of claim 1 , further comprising at least one fluid wall disposed in the space between the inner and outer walls, the at least one fluid wall forming the fluid lumen.

4 . The system of claim 1 , wherein the manifold is formed from the inner wall and the outer wall.

5 . The system of claim 1 , wherein the first fluid port and the second fluid port are formed within the inner wall of the manifold.

6 . The system of claim 5 , wherein the inner wall has a first thickness in a first region within the manifold, and a second thickness proximal to the first region.

7 . The system of claim 6 , wherein the first thickness is greater than the second thickness.

8 . The system of claim 7 , wherein the first thickness is about twice that of the second thickness.

9 . The system of claim 6 , wherein the first thickness ranges from 0.10 mm to 0.60 mm and the second thickness ranges from 0.20 mm to 0.70 mm.

10 . The system of claim 6 , wherein the first thickness is selected to provide a generally laminar flow for the respective fluid streams.

11 . The system of claim 1 , wherein a cross-sectional dimension of the first fluid port and the second fluid port varies along its length.

12 . The system of claim 11 , wherein the first fluid port and the second fluid port are conical along their lengths.

13 . The system of claim 12 , wherein a smallest dimension of the first fluid port and the second fluid port is positioned at a distal end of the two or more ports.

14 . The system of claim 1 , wherein the manifold is configured to increase a flow rate of the fluid in the fluid lumen.

15 . The system of claim 1 , wherein the manifold is configured to increase a pressure of the fluid in the fluid lumen.

16 . The system of claim 1 , further comprising a funnel positioned at a distal end of the distal portion, the funnel being configured to engage with the thrombus.

17 . The system of claim 16 , wherein the manifold is disposed proximally of the funnel.

18 . The system of claim 16 , wherein the manifold is integrated into the funnel.

Assignments (1)

Continuity (2)

References Cited (400)