Granted Patent B2

US 12,569,195 · App. 18/651,911 · Granted Mar 10, 2026

Inventors: Amir Belson (Savyon, IL); Keiichiro Ichiryu (Campbell, CA); Zachary Kimura (San Jose, CA); Mark Shughart (Redwood City, CA); Harold Sampson (Sunnyvale, CA); Daren Stewart (Belmont, CA); Eric Storne (Menlo Park, CA); John Tighe (Los Gatos, CA)

Assignee: Stryker Corporation

A61B5/4848A41D1/002A61B5/00A61B5/0002A61B5/0004A61B5/002A61B5/1121A61B5/4528A61B5/4585A61B5/4878G06F3/0481A41D13/1281A61B2505/09G06F3/0484

Abstract

Claims (35)

1 . A system for monitoring for the presence of an infection or inflammation in a subject, the system comprising:

at least one adherent sensor configured to be coupled to skin adjacent to a joint of the subject, the at least one adherent sensor configured to sense one or more mechanical measurements about the joint and a temperature of the skin about the joint, wherein one or more mechanical measurements comprises measurements of a stretching or contraction of the at least one adherent sensor, the at least one adherent sensor including a transmitter configured to transmit the sensed mechanical measurements and temperature to a local computing device; and

a remote computing device in communication with the local computing device, the remote computing device comprising a processing device configured to:

receive data from the local computing device concerning the sensed mechanical measurements and temperature,

determine the presence of infection or inflammation by comparing the received data against a baseline for the subject which includes an identity of a coincidence of stretching of the at least one adherent sensor with an increase in sensed temperature; and

transmit an alert to the local computing device if the determination indicates the presence of infection or inflammation,

wherein the system is configured to identify one or more cycles of flexion or extension on the joint, determine one or more impacts on the joint, and determine a gait pattern of the subject based on the identified one or more cycles of flexion and extension and the one or more impacts on the joint; and

wherein the gait pattern is indicated by a coincidence of the one or more cycles of flexion and extension with the one or more impacts on the joint.

2 . The system of claim 1 , wherein the least one adherent sensor comprises a replaceable enclosure and a sensor assembly removable from the enclosure, the replaceable enclosure comprising the adherent surface and the sensor assembly comprising a mechanical sensing element and the transmitter.

3 . The system of claim 1 , wherein the mechanical measurements comprise stretching or shrinkage of the at least one adherent sensor, an oxygenation of tissue adjacent the joint, a humidity of the tissue adjacent the joint, muscle activity of the joint, an electrical impedance of the tissue adjacent the joint, an acoustic impedance of the tissue adjacent the joint, or one or more biomarkers.

4 . The system of claim 1 , wherein the at least one adherent sensor comprises one or more of a strain sensor, a force sensor, a flex sensor, a pressure sensor, an accelerometer, a magnetometer, a gyroscope, a potentiometer, a barometer, a piezoelectric sensor, a pressurized tube sensor, a coiled conductor sensor, a magnetic sensor.

5 . The system of claim 4 , wherein the at least one adherent sensor is configured to measure one or more of an elevation of the adherent sensor, a pitch, roll, or yaw of the adherent sensor, an orientation of the adherent sensor relative to gravity, an orientation of the adherent sensor relative to a paired adherent sensor, an orientation of the adherent sensor relative to the joint, motion of the adherent sensor, motion of the joint, motion of tissue adjacent the joint, a deformation of the adherent sensor, stress on the adherent sensor, or strain on the adherent sensor.

6 . The system of claim 5 wherein the at least one adherent sensor includes at least two adherent sensors.

7 . The system of claim 6 , wherein the least two adherent sensors are configured to communicate with one another wirelessly with a wireless data transfer protocol comprising one or more of Near Field Communication (NFC), wireless USB, ultra-wide-band, ultraband, Wi-Fi, Bluetooth, Bluetooth LE, ZigBee, WiMax, Thread, LoRa, LPWA, an IoT networking protocol, a radio-wave based protocol, a microwave based protocol, an infrared based protocol, or a sound-wave based protocol.

8 . The system of claim 6 , wherein the system is configured to determine one or more of a range of motion of the joint, a range of flexion of the joint, a range of extension of the joint, a range of rotation of the joint, a motion pattern of the joint, a gait of the subject, a position of the joint, an orientation of the joint, a placement of the at least one adherent sensors relative to the joint, a compliance of the subject to a joint cooling or heating protocol, a compliance of the subject to a movement protocol, a compliance of the subject for muscle activation/inactivation swelling of the joint, or a physical therapy progress of the subject.

9 . The system of claim 8 , wherein the system is configured to determine one or more of placements and orientations of the at least two adherent sensors relative to the joint and determine one or more of a range of motion of the joint, a range of flexion of the joint, a range of extension of the joint, a range of rotation of the joint, a motion pattern of the joint, a gait of the subject, a position of the joint, or an orientation of the joint based on the determined placement and orientations of the at least two adherent sensors relative to the joint.

10 . The system of claim 1 , wherein the system is configured to monitor the gait pattern for one or more gait inconsistencies.

11 . The system of claim 10 , wherein determining the gait pattern comprises distinguishing walking of the subject from a free movement of the joint of the subject.

12 . The system of claim 11 , wherein the joint comprises one or more of a hip, a knee, or an ankle of the subject.

13 . The system of claim 12 , wherein determining the elevation of the joint comprises detecting and comparing relative positions of the at least two adherent sensors.

14 . A method for monitoring for the presence of an infection or inflammation in a subject, the method comprising:

collecting mechanical measurements and a skin temperature with at least one adherent sensor coupled to skin adjacent to a joint of the subject, wherein the mechanical measurements comprises measurements of a stretching or contraction of the at least one adherent sensor, wherein the adherent sensor comprises a transmitter;

transmitting the mechanical measurements and temperature to a local computing device;

receiving data with a remote computing device from the local computing device, the data concerning the mechanical measurements and temperature;

determining the presence of infection or inflammation by comparing the received data against a baseline for the subject which includes an identity of a coincidence of stretching of the at least one adherent sensor with an increase in collected skin temperature; and

transmitting an alert to the local computing device if the determination indicates the presence of infection or inflammation,

wherein the method further comprises identifying one or more cycles of flexion or extension on the joint, determining one or more impacts on the joint, and determining a gait pattern of the subject based on the identified one or more cycles of flexion and extension and the one or more impacts on the joint; and

wherein the gait pattern is indicated by a coincidence of the one or more cycles of flexion and extension with the one or more impacts on the joint.

15 . The method of claim 14 , wherein the least one adherent sensor comprises a replaceable enclosure and a sensor assembly removable from the enclosure, the replaceable enclosure comprising the adherent surface and the sensor assembly comprising a mechanical sensing element and the transmitter; and wherein the mechanical measurements comprise stretching or shrinkage of the at least one adherent sensor, an oxygenation of tissue adjacent the joint, a humidity of the tissue adjacent the joint, muscle activity of the joint, an electrical impedance of the tissue adjacent the joint, an acoustic impedance of the tissue adjacent the joint, or one or more biomarkers.

16 . The method of claim 14 , wherein:

the at least one adherent sensor comprises one or more of a strain sensor, a force sensor, a flex sensor, a pressure sensor, an accelerometer, a magnetometer, a gyroscope, a potentiometer, a barometer, a piezoelectric sensor, a pressurized tube sensor, a coiled conductor sensor, a magnetic sensor; and

the at least one adherent sensor is configured to measure one or more of an elevation of the adherent sensor, a pitch, roll, or yaw of the adherent sensor, an orientation of the adherent sensor relative to gravity, an orientation of the adherent sensor relative to a paired adherent sensor, an orientation of the adherent sensor relative to the joint, motion of the adherent sensor, motion of the joint, motion of tissue adjacent the joint, a deformation of the adherent sensor, stress on the adherent sensor, or strain on the adherent sensor.

17 . The method of claim 14 wherein, the at least one adherent sensor includes at least two adherent sensors configured to communicate with one another wirelessly with a wireless data transfer protocol comprising one or more of Near Field Communication (NFC), wireless USB, ultra-wide-band, ultraband, Wi-Fi, Bluetooth, Bluetooth LE, ZigBee, WiMax, Thread, LoRa, LPWA, an IoT networking protocol, a radio-wave based protocol, a microwave based protocol, an infrared based protocol, or a sound-wave based protocol.

18 . The method of claim 17 , further comprising determining, with the remote computing device, one or more of a range of motion of the joint, a range of flexion of the joint, a range of extension of the joint, a range of rotation of the joint, a motion pattern of the joint, a gait of the subject, a position of the joint, an orientation of the joint, a placement of the at least one adherent sensors relative to the joint, a compliance of the subject to a joint cooling or heating protocol, a compliance of the subject to a movement protocol, a compliance of the subject for muscle activation/inactivation swelling of the joint, the one or more impacts on the joint, or a physical therapy progress of the subject.

19 . The method of claim 18 , further comprising determining one or more of placements and orientations of the at least two adherent sensors relative to the joint and determining one or more of a range of motion of the joint, a range of flexion of the joint, a range of extension of the joint, a range of rotation of the joint, a motion pattern of the joint, a gait of the subject, a position of the joint, or an orientation of the joint based on the determined placement and orientations of the at least two adherent sensors relative to the joint.

Assignments (2)

Continuity (7)

References Cited (400)