Granted Patent
B2
US 8,318,951 · App. 13/116,574 · Granted Nov 27, 2012
Stem cell differentiating agents and uses therefor
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Abstract
The present invention relates to screens for compounds that can induce stem cell differentiation. In addition, isoxazoles and sulfonyl hydrazones are identified as general classes of compounds that can induce differentiation of stem cells into cells of neuronal and cardiac fate, respectively.
Claims (4)
1. A compound having the formula:
wherein X is NH, Y is O and R is substituted or unsubstituted C 1 -C 6 alkenyl or a substituded or unsubstituted C 2 -C 6 alkynyl.
2. The compound of claim 1 , wherein R is a substituted or unsubstituted C 2 -C 6 alkenyl.
3. The compound of claim 1 , wherein R is a substituted or unsubstituted C 2 -C 6 alkynyl.
Assignments (1)
CONFIRMATORY LICENSE
Recorded Jun 21, 2011
From: THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 026468/0561 →
Continuity (4)
Provisional Application
60953182
· Jul 31, 2007