IP Library Granted Patent US 8,337,862
Granted Patent B2
US 8,337,862 · App. 12/506,622 · Granted Dec 25, 2012

Method for treating knee joint pain caused by saphenous nerve entrapment

Assignee: Ipsen Biopharm Limited
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Quick Facts
Patent No.
US 8,337,862
App. No.
12/506,622
Granted
Dec 25, 2012
Kind
B2
Abstract

A method using a pharmaceutical composition comprising botulinum toxin and a pharmacologically acceptable carrier to treat pain in the knee joint caused by saphenous nerve entrapment. The composition of the present invention is for subcutaneous injection above the medial side of the knee.

Claims (7)

1. A method for treating knee joint pain caused by saphenous nerve entrapment in a subject, the method comprising:

identifying at least one area having abnormal hypersensitive receptors by pinching the skin of the subject with saphenous nerve entrapment where the saphenous nerve passes underneath,

providing a pharmaceutical composition comprising about 40 to 70 LD50 units of a botulinum toxin and a pharmacologically acceptable carrier; and

injecting 5 or 10 LD50 units of the pharmaceutical composition subcutaneously into multiple points in said at least one area having abnormal hypersensitive receptors, thereby removing the pain immediately by normalization of the hypersensitive receptors.

2. The method of claim 1 , wherein the botulinum toxin is a botulinum toxin Type A.

3. The method of claim 1 , wherein said multiple points are 5 to 12 points.

4. The method of claim 1 , wherein the pharmaceutical composition comprises about 60 LD 50 units of the botulinum toxin.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 27, 2010
From: IPSEN DEVELOPMENTS LIMITED
To: IPSEN BIOPHARM LIMITED
Reel/Frame 024452/0646 →
CHANGE OF NAME Recorded Feb 18, 2010
From: IPSEN LIMITED
To: IPSEN DEVELOPMENTS LIMITED
Reel/Frame 023958/0182 →
Priority Claims (1)
KR 2004-48889 · Jun 28, 2004 · national
Continuity (2)
Division 11630099
Related Publication 20090317426A1 · Dec 24, 2009