IP Library Granted Patent US 8,821,853
Granted Patent B2
US 8,821,853 · App. 14/150,076 · Granted Sep 2, 2014

Anti-fatty liver agent

Inventors: Hiroshi Kawakami (Saitama, JP); Hiroaki Matsuyama (Saitama, JP); Masao Sato (Fukuoka, JP); Katsumi Imaizumi (Fukuoka, JP)
Assignee: Megmilk Snow Brand Co., Ltd.
A61K35/747A23L1/3014A23L2/52C12R1/225A61K2035/11A61K9/19
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Quick Facts
Patent No.
US 8,821,853
App. No.
14/150,076
Granted
Sep 2, 2014
Kind
B2
Abstract

An anti-fatty liver agent containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient is provided. Also disclosed is a pharmaceutical agent having an anti-fatty liver activity or an anti-fatty liver beverage or food containing a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri as an active ingredient. Methods of treating fatty liver in a subject by administering a cell and/or a culture of the lactic acid bacterium Latobacillus gasseri are also provided.

Claims (15)

1. A method of treating fatty liver in a subject in need thereof, comprising administering to the subject an effective amount of lyophilized viable Lactobacillus gasseri cells.

2. The method of claim 1 , comprising administering to the subject a food or beverage comprising the Lactobacillus gasseri cells.

3. The method of claim 1 , wherein the Lactobacillus gasseri is any one of Lactobacillus gasseri SBT2055 (FERM P-15535) and Lactobacillus gasseri SBT0274 (FERM P-17784).

4. The method of claim 1 , wherein the Lactobacillus gasseri cells are administered to the subject orally.

5. The method of claim 1 , wherein the effective amount of Lactobacillus gasseri cells administered to the subject is 0.5 to 50 g dry weight per day.

6. A method for reducing triglyceride levels in the liver of a subject having fatty liver disease, comprising administering to the subject an effective amount of lyophilized viable Lactobacillus gasseri cells.

7. The method of claim 6 , comprising administering to the subject a food or beverage comprising the Lactobacillus gasseri cells.

8. The method of claim 6 , wherein the Lactobacillus gasseri is any one of Lactobacillus gasseri SBT2055 (FERM P-15535) and Lactobacillus gasseri SBT0274 (FERM P-17784).

9. The method of claim 6 , wherein the Lactobacillus gasseri cells are administered to the subject orally.

10. The method of claim 6 , wherein the effective amount of Lactobacillus gasseri cells administered to the subject is 0.5 to 50 g dry weight per day.

11. A method for reducing the amount of liver fat in a subject having fatty liver disease, comprising administering to the subject an effective amount of lyophilized viable Lactobacillus gasseri cells.

12. The method of claim 11 , comprising administering to the subject a food or beverage comprising the Lactobacillus gasseri cells.

13. The method of claim 11 , wherein the Lactobacillus gasseri is any one of Lactobacillus gasseri SBT2055 (FERM P-15535) and Lactobacillus gasseri SBT0274 (FERM P-17784).

14. The method of claim 11 , wherein the Lactobacillus gasseri cells is are administered to the subject orally.

15. The method of claim 11 , wherein the effective amount of Lactobacillus gasseri cells administered to the subject is 0.5 to 50 g dry weight per day.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2014
From: KAWAKAMI, HIROSHI; MATSUYAMA, HIROAKI; SATO, MASAO; IMAIZUMI, KATSUMI
To: SNOW BRAND MILK PRODUCTS CO., LTD
Reel/Frame 031917/0548 →
CHANGE OF NAME Recorded Jan 8, 2014
From: SNOW BRAND MILK PRODUCTS CO., LTD.
To: MEGMILK SNOW BRAND CO., LTD.
Reel/Frame 031917/0739 →
Priority Claims (1)
JP 2006-201733 · Jul 25, 2006 · national
Continuity (2)
Continuation In Part 12375097
Related Publication 20140140972A1 · May 22, 2014