IP Library Granted Patent US 8,980,307
Granted Patent B2
US 8,980,307 · App. 13/929,251 · Granted Mar 17, 2015

Compositions and methods for the sustained release of beta-alanine

Inventors: Roger Harris (New Market, GB); John Wise (San Marcos, CA)
Assignee: Natural Alternatives International, Inc.
A61K9/48A61K31/197A61K9/5015A23L1/3051A61K9/06A61K9/0095A61K31/445A61K9/4858
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Quick Facts
Patent No.
US 8,980,307
App. No.
13/929,251
Granted
Mar 17, 2015
Kind
B2
Abstract

Methods and compositions are provided for increasing the anaerobic working capacity of muscle and other tissues. Also provided are compositions formulated for the sustained release of free beta-alanine. Also provided is a dietary supplement formulated, for example, as a solid food product, an edible suspension, liquid or semi-liquid as described herein.

Claims (15)

1. A human dietary supplement comprising free beta-alanine or a salt of free beta-alanine,

wherein the free beta-alanine or the salt of free beta-alanine comprised in the human dietary supplement is formulated for sustained release; and the free beta-alanine or the salt of free beta-alanine is encapsulated by a coating agent to form an encapsulated product;

wherein the encapsulated product contains from about 0.1 g to about 10.0 g of the free beta-alanine or the salt of free beta-alanine per serving; and

wherein the human dietary supplement decreases the effects of paraesthesia, and delivers an effective amount of the free beta-alanine or the salt of free beta-alanine to increase tissue anaerobic working capacity when provided over a prolonged period of time.

2. The human dietary supplement of claim 1 , wherein the encapsulated product contains from about 1.0 g to about 10.0 g of the free beta-alanine or the salt of free beta-alanine per serving.

3. The human dietary supplement of claim 1 , wherein the encapsulated product contains from about 2.0 g to about 8.0 g of the free beta-alanine or the salt of free beta-alanine per serving.

4. The human dietary supplement of claim 1 , wherein the encapsulated product contains from about 3.0 g to about 7.0 g of the free beta-alanine or the salt of free beta-alanine per serving.

5. The human dietary supplement of claim 1 , wherein the encapsulated product contains from about 4.0 g to about 6.0 g of the free beta-alanine or the salt of free beta-alanine per serving.

6. The human dietary supplement of claim 1 , further comprising one or more additional components selected from the group consisting of vitamins, lipids, carbohydrates, amino acids, trace elements, colorings, flavors, artificial sweeteners, natural health improving substances, antioxidants, stabilizers, preservatives and buffers.

7. The human dietary supplement of claim 6 , wherein the free beta-alanine or the salt of free beta-alanine is contained in a layer separate from other ingredients of the human dietary supplement.

8. The human dietary supplement of claim 1 , wherein the supplement is in a liquid or semi-liquid form.

9. The human dietary supplement of claim 1 , further comprising creatine.

10. The human dietary supplement of claim 1 , further comprising one or more additional amino acids.

11. The human dietary supplement of claim 10 , wherein the one or more additional amino acids are selected from the group consisting of: L-cysteine and L-citrulline.

12. The human dietary supplement of claim 1 , further comprising one or more acetylcholine precursors selected from the group consisting of: choline chloride and phosphatidylcholine.

Assignments (2)
SECURITY INTEREST Recorded May 18, 2026
From: NATURAL ALTERNATIVES INTERNATIONAL, INC.
To: LEGACY CORPORATE LENDING, LLC, AS ADMINISTRATIVE AGENT
Reel/Frame 074684/0430 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2015
From: HARRIS, ROGER; WISE, JOHN
To: NATURAL ALTERNATIVES INTERNATIONAL, INC.
Reel/Frame 035073/0519 →
Continuity (5)
Continuation 13755954 · Jan 31, 2013
Continuation 13646184 · Oct 5, 2012
Division 12064005
Provisional Application 60683985 · May 23, 2005
Related Publication 20140017293A1 · Jan 16, 2014