Modified saponins for the treatment of fungal infections

1. A method of treating a fungal infection in a subject, the method comprising administering to the subject a therapeutically effective amount of a compound of Formula II:

or a pharmaceutically acceptable salt thereof, wherein:

R 1 is H or OC(O)R A ;

R 2 is H or OH;

R 3 is H, C(O)OR A , CH 2 OR A , CH 2 OC(O)R A ;

R 4 and R 5 are each independently H or OC(O)R B ;

R A is H or C 1-6 alkyl;

R B is C 2-6 alkenyl; and

Gly is

2. The method of claim 1 , wherein the compound is:

or a pharmaceutically acceptable salt thereof.

3. The method of claim 1 , wherein the compound is:

or a pharmaceutically acceptable salt thereof.

4. The method of claim 1 , wherein the compound is:

or a pharmaceutically acceptable salt thereof.

5. The method of claim 1 , wherein the compound is:

or a pharmaceutically acceptable salt thereof.

6. The method of claim 1 , wherein the fungal infection is infection with a Candida species fungus.