IP Library Granted Patent US 9,482,652
Granted Patent B2
US 9,482,652 · App. 14/023,111 · Granted Nov 1, 2016

Method of automated calibration and diagnosis of laboratory instruments

Inventors: Bruce E. DeSimas (Danville, CA); Leslie A. Dow (Palo Alto, CA)
Assignee: Applied Biosystems, LLC
G01N33/00G01D18/002G01N31/00Y10S707/99933Y10S707/99942Y10T436/10
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Quick Facts
Patent No.
US 9,482,652
App. No.
14/023,111
Granted
Nov 1, 2016
Kind
B2
Abstract

Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.

Claims (17)

1. A non-transitory computer storage medium containing computer instructions stored therein for causing a computer processor to perform:

providing a laboratory instrument adapted to image a multi-well plate;

performing a plurality of calibration tests sequentially on the laboratory instrument, wherein an expert knowledge system automates the sequence of calibration tests;

verifying the progress of the calibration tests by applying at least one expert knowledge based test; and

reporting the status of the calibration test as a result of the at least one expert knowledge based test.

2. The computer storage medium of claim 1 containing instructions for performing method steps for calibrating a laboratory instrument, wherein the multi-well plate contains fluorescent dyes.

3. The computer storage medium of claim 1 containing instructions for performing method steps for calibrating a laboratory instrument, wherein verifying the progress comprises applying at least one expert knowledge based test to verify that a correct multi-well plate was installed.

4. A non-transitory computer storage medium containing computer instructions stored therein for causing a computer processor to perform:

providing a laboratory instrument adapted to image a multi-well plate;

analyzing data generated using the multi-well plate on the laboratory instrument, wherein the data analysis is automated with an expert knowledge system;

verifying the progress of the data analysis by applying at least one expert knowledge based test; and

reporting the status of the data analysis as a result of the at least one expert knowledge based test.

5. A non-transitory computer storage medium containing computer instructions stored therein for causing a computer processor to perform:

providing a laboratory instrument adapted to image a multi-well plate;

performing a plurality of instrument function tests on the laboratory instrument, wherein the instrument function tests are automated with an expert knowledge system;

verifying the progress of the instrument function test by applying at least one expert knowledge based test; and

reporting the status of the instrument function test as a result of the at least one expert knowledge based test.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2016
From: DESIMAS, BRUCE E.; DOW, LESLIE A.
To: APPLERA CORPORATION
Reel/Frame 039607/0371 →
CHANGE OF NAME Recorded Aug 31, 2016
From: APPLERA CORPORATION
To: APPLIED BIOSYSTEMS INC.
Reel/Frame 039607/0403 →
MERGER AND CHANGE OF NAME Recorded Aug 31, 2016
From: APPLIED BIOSYSTEMS INC.; ATOM ACQUISITION CORPORATION WITH AND INTO APPLIED BIOSYSTEMS INC.
To: APPLIED BIOSYSTEMS INC.
Reel/Frame 039607/0420 →
MERGER AND CHANGE OF NAME Recorded Aug 31, 2016
From: APPLIED BIOSYSTEMS INC.; APPLIED BIOSYSTEMS, LLC
To: APPLIED BIOSYSTEMS, LLC
Reel/Frame 039607/0439 →
Continuity (6)
Continuation 13874241 · Apr 30, 2013
Continuation 13359813 · Jan 27, 2012
Continuation 12632742 · Dec 7, 2009
Continuation 11469308 · Aug 31, 2006
Provisional Application 60713568 · Sep 1, 2005
Related Publication 20140122006A1 · May 1, 2014