IP Library › Granted Patent US 9,504,701
Granted Patent B2
US 9,504,701 · App. 14/941,340 · Granted Nov 29, 2016

Methods for treating viral infections using hydrogen sulfide donors

Inventors: Antonella Casola (Galveston, TX); Olivier Escaffre (Galveston, TX); Alexander N. Freiberg (League City, TX); Roberto P. Garofalo (Galveston, TX)
Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
A61K31/675A61K31/10A61K31/385A61K31/404A61K31/5375A61K33/04A61K45/06
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Quick Facts
Patent No.
US 9,504,701
App. No.
14/941,340
Granted
Nov 29, 2016
Kind
B2
Abstract

Certain embodiments are directed to methods of treating respiratory infection by administering an H 2 S donor.

Claims (7)

1. A method for treating a filoviridae viral infection of a subject comprising administering an effective amount of an H 2 S donor to the subject.

2. The method of claim 1 , wherein the viral infection is an Ebola virus infection.

3. The method of claim 1 , wherein the H 2 S donor is administered by inhalation or inspiration into the respiratory tract.

4. The method of claim 1 , wherein the H 2 S donor is a slow release H 2 S donor.

5. The method of claim 1 , wherein the slow release H 2 S donor is administered in combination with a fast release H 2 S donor.

6. The method of claim 1 , wherein the H 2 S donor is Gyy4137, ACS67, diallyl trisulfide, NaHS, ATB-343, ATB-337, or AP67.

7. The method of claim 1 , wherein the H 2 S donor is Gyy4137 or AP67.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 2, 2016
From: CASOLA, ANTONELLA; ESCAFFRE, OLIVIER S.B.; FREIBERG, ALEXANDER N.; GAROFALO, ROBERTO P.
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 039623/0910 →
Continuity (3)
Continuation In Part 14728737 · Jun 2, 2015
Provisional Application 62006680 · Jun 2, 2014
Related Publication 20160058779A1 · Mar 3, 2016