Color changing polymer films for detecting chemical and biological targets
A sensor system, and a method of detecting a target analyte, comprises a chemically functionalized block copolymer, and a target analyte. The block copolymer exhibits a color change in the visible spectrum upon exposure to the target analyte.
1. A method of providing a sensor system for detecting a target analyte, comprising the steps of:
providing a block copolymer, the block copolymer having a lamellar morphology including at least two layers;
functionalizing the block copolymer; and
linking an antibody to the functionalized block copolymer, wherein the antibody is capable of binding a moiety of a target analyte, and wherein the distance between the layers changes upon exposure to and selective recognition of the target analyte by the antibody so that the functionalized block copolymer exhibits a shift in peak wavelength in the visible spectrum.
2. The method of claim 1 , wherein the block copolymer is 2-vinyl pyridine.
3. The method of claim 2 , wherein the 2-vinyl pyridine block copolymer is functionalized with 2-bromomethylphenylboronic acid or bromoethylamine.
4. The method of claim 1 , wherein the target analyte is selected from the group consisting of glucose, fructose, galactose and mannose.
5. The method of claim 1 , wherein the target analyte is selected from the group consisting of a foodborne pathogen, a toxin, and an explosive compound.
6. The method of claim 5 , wherein the foodborne pathogen is selected from the group consisting of Escherichia coli, Listeria , and Salmonella.
7. The method of claim 5 , wherein the toxin is selected from the group consisting of ricin, sarin, and soman.
8. The method of claim 5 , wherein the explosive compound is selected from the group consisting of nitroglycerin and triacetone triperoxide.
9. The method of claim 1 , comprising the further step of coupling the functionalized block copolymer to a textile material.