IP Library › Granted Patent US 10,106,599
Granted Patent B2
US 10,106,599 · App. 15/808,807 · Granted Oct 23, 2018

Antibody and antibody-containing composition

Inventor: Yasuhiro Tsukamoto (Osaka, JP)
Assignees: Ostrich Pharma KK; Immortal Spirit Limited
C07K16/1271C07K16/084C07K16/085C07K16/1045C07K16/1063C07K16/1267C07K2317/11C07K2317/23C07K2317/76C12N2710/14043
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Quick Facts
Patent No.
US 10,106,599
App. No.
15/808,807
Granted
Oct 23, 2018
Kind
B2
Abstract

For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substances released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.

Claims (10)

1. A method of treating atopy of a subject, comprising administering a composition comprising ostrich polyclonal antibodies against antigens from a lysis solution of a microbial cell to the subject, wherein the microbial cell comprises Staphylococcus aureus and the antibodies are produced by immunizing an ostrich with the lysis solution of the microbial cell, and obtaining the antibodies from an egg of the ostrich.

2. The method of claim 1 , wherein the antibodies are polyclonal IgY antibodies.

3. The method of claim 1 , wherein the composition further comprises ostrich polyclonal antibodies against antigens from a lysis solution of Propionibacterium acnes.

4. The method of claim 1 or claim 3 , wherein the antigens comprise one or more of enterotoxin, TSST-1, coagulase, and protease.

5. The method of claim 1 or claim 3 , wherein the composition comprises a base.

6. A method of treating acne of a subject, comprising administering a composition comprising ostrich polyclonal antibodies against antigens from a lysis solution of a microbial cell to the subject, wherein the microbial cell comprises Propionibacterium acnes and the antibodies are produced by immunizing an ostrich with the lysis solution of the microbial cell, and obtaining the antibodies from an egg of the ostrich.

7. The method of claim 6 , wherein the antibodies are polyclonal IgY antibodies.

8. The method of claim 6 , wherein the composition further comprises ostrich polyclonal antibodies against antigens from a lysis solution of Staphylococcus aureus.

9. The method of claim 8 , wherein the antigens comprise one or more of enterotoxin, TSST-1, coagulase, and protease.

10. The method of claim 6 or claim 8 , wherein the composition comprises a base.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2024
From: IMMORTAL SPIRIT LIMITED
To: ZEAL COSMETICS INC.
Reel/Frame 067214/0842 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 13, 2018
From: TSUKAMOTO, YASUHIRO
To: OSTRICH PHARMA KK; IMMORTAL SPIRIT LIMITED
Reel/Frame 046632/0460 →
Priority Claims (1)
JP 2011-179378 · Aug 19, 2011 · national
Continuity (3)
Continuation 15230188 · Aug 5, 2016
Division 14239776
Related Publication 20180066042A1 · Mar 8, 2018
Cited By (1)
US 12,302,685