Method for improving gingivitis and periodontitis by antibacterial, antioxidant and anti-inflammatory effects and inhibition of alveolar bone loss of complex extracts of moringa leaf and eucommia bark
The present invention relates to a method for preventing, improving or treating a periodontal disease, by administering a composition containing a moringa extract and a eucommia bark extract as active ingredients. More specifically, the complex composition of a moringa extract and a eucommia bark extract according to the present invention provides a synergistic effect in improvement of a periodontal disease including gingivitis and periodontitis. Especially, it exhibits an effect of directly preventing or improving a periodontal disease through antioxidant, antibacterial or anti-inflammatory effect, improvement of alveolar bone loss and regeneration of alveolar bone, etc. Accordingly, it can be usefully used as a food, a medicine, a quasi-drug, etc.
1. A method of improving or treating a periodontal disease in an individual, comprising administering a composition comprising a moringa extract and a eucommia bark extract as active ingredients to the individual,
wherein a weight ratio of the moringa extract and the eucommia bark extract is 2:1 to 4:1 ( moringa extract: eucommia bark extract).
2. The method according to claim 1 , wherein the composition is a food or pharmaceutical composition.
3. The method according to claim 1 , wherein the moringa extract is a moringa leaf extract.
4. The method according to claim 1 , wherein the moringa extract and the eucommia bark extract are prepared by using water, a C 1 -C 4 lower alcohol or a mixture thereof as an extraction solvent.
5. The method according to claim 1 , wherein the periodontal disease is gingivitis or periodontitis.
6. The method according to claim 1 , wherein the composition further comprises one or more extract selected from a group consisting of pomegranate, balloon flower root, gardeniae fructus, scutellariae radix, lotus leaf, Chinese mulberry leaf, ginger, peony root, achyranthis radix, red clover, dandelion and dandelion root extracts as an active ingredient.
7. The method according to claim 6 , wherein the pomegranate extract comprises 0.5-3 mg/g of ellagic acid.
8. The method according to claim 6 , wherein the balloon flower root, gardeniae fructus, scutellariae radix, lotus leaf, Chinese mulberry leaf, ginger, peony root, achyranthis radix, red clover, dandelion and dandelion root extracts are prepared by using water, a C 1 -C 4 lower alcohol or a mixture thereof as an extraction solvent.