Granted Patent
B2
US 10,167,260 · App. 15/639,824 · Granted Jan 1, 2019
2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors
Assignee:
Northwestern University
View Patent ↗
Loading inventors, assignments & file history…
Abstract
Aminopyridine compounds, as can be used in conjunction with methods for modulation of nitric oxide synthase activity.
Claims (5)
1. A compound selected from compounds of a formula
wherein X is selected from N and CH; L is selected from (OCH 2 ) n and CH 2 NH(CH 2 ) n moieties, and n is an integer selected from 1-3; and R 1 is selected from amino, pyridin-2-yl, pyridin-4-yl, piperidin-4-yl, phenyl, fluorophenyl and chlorophenyl moieties, and salts thereof.
2. The compound of claim 1 , wherein X is N and L is a CH 2 NH(CH 2 ) n moiety.
3. The compound of claim 1 , wherein said compound is an ammonium salt.
4. The compound of claim 3 , wherein said ammonium salt has a counter ion that is a conjugate base of a protic acid.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 20, 2017
From: SILVERMAN, RICHARD B.; JING, QING
To: NORTHWESTERN UNIVERSITY
Reel/Frame 043640/0233 →
Continuity (5)
Provisional Application
61774147
· Mar 7, 2013
Cited By (2)