IP Library Granted Patent US 10,300,028
Granted Patent B2
US 10,300,028 · App. 15/124,321 · Granted May 28, 2019

Composition and method for enhancing wound healing

Inventor: Mark Tuffley (Brisbane, AU)
A61K31/155A61K9/0014A61K31/145A61K31/164A61K31/185A61K31/19A61K31/197A61K31/198A61K31/205A61K31/375A61K31/4188A61K31/4415A61K31/455A61K31/51A61K31/519A61K31/525A61K31/555A61K31/59A61K31/7004A61K31/714A61K31/733A61K33/00A61K33/04A61K33/06A61K33/10A61K33/14A61K33/18A61K33/24A61K33/30A61K33/32A61K33/34A61K45/06
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,300,028
App. No.
15/124,321
Granted
May 28, 2019
Kind
B2
Abstract

The invention relates to a composition for enhancing wound healing and/or for reducing pain and inflammation, comprising a first active ingredient and a second active ingredient, wherein the first active ingredient comprises an antiseptic and the second active ingredient comprises an admixture of at least one vitamin, at least one mineral and at least one amino acid, and to use of the composition for enhancing wound healing.

Claims (20)

1. A method for enhancing wound healing and/or reducing pain and inflammation in a subject, said method comprising the steps of administering to a wound of the subject a therapeutically effective amount of a composition comprising a first active ingredient and a second active ingredient, wherein the first active ingredient comprises an antiseptic and the second active ingredient comprises an admixture of carbohydrates, amino acids, at least one vitamin and at least one mineral, wherein the carbohydrates comprise dextrose, fructose and inulin, the amino acids comprise glycine, arginine, glutamine and lysine, wherein the glycine is present in the composition in an amount that is greater than the amount of arginine in the composition.

2. The method of claim 1 , wherein said administration is topical administration.

3. The method of claim 1 , wherein the dextrose is present in an amount of from 800 mg to 1200 mg per 7 grams of the composition, the fructose is present in an amount of from 200 mg to 300 mg per 7 grams of the composition, and the inulin is present in an amount of from 400 to 600 mg per 7 grams of the composition.

4. The method of claim 1 , wherein the glutamine is present in an amount of from 100 mg to 200 mg per 7 grams of the composition, the lysine is present in an amount of from 20 mg to 100 mg per 7 grams of the composition, the arginine is present in an amount of from 10 mg to 30 mg per 7 grams of the composition, and the glycine is present in an amount to give a ratio of glycine to arginine in the range of from 19:1 to 18:1 by weight.

5. The method according to claim 1 , wherein said antiseptic is a bis-biguanide compound.

6. The method according to claim 5 , wherein said bis-biguanide compound is chlorhexidine or a chlorhexidine salt.

7. The method according to claim 6 , wherein the chlorhexidine is chlorhexidine-digluconate.

8. The method according to claim 1 , wherein the first active ingredient comprises a bis-biguanide compound at a concentration of 0.01% to 3% by weight.

9. The method according to claim 1 , wherein said antiseptic is iodine.

10. The method according to claim 1 , wherein said antiseptic is an antibacterial dye.

11. The method according to claim 1 , wherein said antiseptic is a halogenated phenol.

12. The method according claim 1 , wherein said antiseptic is a quinolone.

13. The method according to claim 1 , wherein the mineral is selected from the group consisting of sodium, magnesium, potassium, calcium, zinc, manganese, copper, molybdenum, selenium and chromium or combination thereof.

14. The method according to claim 1 , wherein the vitamin is selected from the group consisting of thiamine, riboflavin, niacin, vitamin C, vitamin D, vitamin E, vitamin B, vitamin B12, pantothenic acid, biotin and folate or combination thereof.

15. The method according to claim 1 , wherein the second active ingredient further comprises a component selected from, the group consisting of carnitine, glucosamine, taurine, sodium citrate, flaxseed oil and micellular casein or combination thereof.

16. The method according to claim 1 , wherein the second active ingredient consists essentially of sodium chloride, magnesium gluconate, potassium chloride, selenium, zinc, sulphate, manganese sulphate, copper sulphate, chromium picolinate, sodium molybdate, potassium iodide, calcium lactate, sodium bicarbonate, L-glycine, L-glutamine, L-lysine, L-arginine, L-carnitine, vitamin C, vitamin D, vitamin B12, niacin, panthothenic acid, riboflavin, pyridoxine, thiamine, folate, biotin, taurine, dextrose, inulin, fructose, dextrose and glycine.

17. The method according to claim 1 , wherein the first active ingredient and the second active ingredient are present at a ratio of 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4 or 1:5.

18. The method of claim 1 , wherein the wound is the result of infection or inflammation.

19. The method of claim 1 , wherein the wound is selected from the group consisting of surgical wound, traumatic mouth ulcer, non-healing area of the mouth, inflammatory lesion and apthous ulcer.

20. The method of claim 17 , wherein the first active ingredient and the second active ingredient are present at a ratio of 1:1.

Priority Claims (1)
AU 2014900780 · Mar 7, 2014 · national
Continuity (1)
Related Publication 20170014358A1 · Jan 19, 2017
Cited By (2)
US 12,324,848 US 12,350,354