IP Library Granted Patent US 10,322,293
Granted Patent B2
US 10,322,293 · App. 16/159,748 · Granted Jun 18, 2019

Systems and methods for fast and reversible nerve block

Inventors: Hillel Chiel (Cleveland, OH); Niloy Bhadra (Cleveland, OH); Mike Jenkins (Cleveland, OH); Emilie Lothet (Cleveland, OH); Tina Vrabec (Cleveland, OH); Kevin Kilgore (Cleveland, OH); Narendra Bhadra (Cleveland, OH); Eric Duco Jansen (Cleveland, OH)
Assignees: CASE WESTERN RESERVE UNIVERSITY; VANDERBILT UNIVERSITY
A61N1/403A61F7/007A61N1/06A61N1/28A61N1/36067A61N1/36071A61N5/0622A61N5/0625A61N7/02A61F2007/0071A61N2005/067A61N2005/0659A61N2007/0021
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Quick Facts
Patent No.
US 10,322,293
App. No.
16/159,748
Granted
Jun 18, 2019
Kind
B2
Abstract

One aspect of the present disclosure relates a system that can quickly and reversibly block conduction in a nerve. The system can include a first nerve block modality that provides heat to the nerve to block conduction in the nerve. For example, the heat can provide the quick nerve block. The system can also include a second nerve block modality that provides an electrical signal to the nerve to block the conduction in the nerve. For example, the electrical signal can provide the reversibility. In some instances, the heat can be provided by an infrared light signal and the electrical signal can be provided by a kilohertz frequency alternating current (KHFAC) signal or a direct current (DC) signal.

Claims (6)

1. A neural prosthetic device, comprising:

an optrode that provides a heat signal to a nerve causing the spasticity to block conduction in the nerve; and

an electrode that provides an electrical signal to the nerve to block the conduction in the nerve,

wherein a timing of the heat signal and another timing of the electrical signal are defined by a control device linked to the optrode and the electrode such that the heat signal and the electrical signal are applied simultaneously for a first period of 1 second or less so that the heat signal blocks an onset response in the nerve generated by the electrical signal, and after the first period of 1 second or less, the heat signal is stopped and the electrical signal is applied alone over a second period of at least one minute after the onset response.

2. The neural prosthetic device of claim 1 , wherein the optrode and the electrode are combined in a single device.

3. The neural prosthetic device of claim 1 , wherein the optrode and the electrode are combined in a single device.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 15, 2018
From: CHIEL, HILLEL; LOTHET, EMILIE; JENKINS, MIKE; VRABEC, TINA; KILGORE, KEVIN; BHADRA, NILOY; BHADRA, NARENDRA
To: CASE WESTERN RESERVE UNIVERSITY
Reel/Frame 047156/0946 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 15, 2018
From: JANSEN, E. DUCO
To: VANDERBILT UNIVERSITY
Reel/Frame 047156/0984 →
Continuity (3)
Division 15126610
Provisional Application 61954915 · Mar 18, 2014
Related Publication 20190046807A1 · Feb 14, 2019
Cited By (2)
US 12,370,079 US 12,496,216