IP Library Granted Patent US 10,385,037
Granted Patent B2
US 10,385,037 · App. 15/887,838 · Granted Aug 20, 2019

4′-O-substituted isoindoline derivatives and compositions comprising and methods of using the same

Inventors: Alexander L. Ruchelman (Cream Ridge, NJ); George W. Muller (Rancho Santa Fe, CA); Hon-Wah Man (Princeton, NJ); Roger Shen-Chu Chen (Edison, NJ)
Assignee: Celgene Corporation
C07D401/04A61K31/454A61K31/4709A61K38/00A61K39/0011A61K45/06C07D401/14C07D405/14C07D409/14
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Quick Facts
Patent No.
US 10,385,037
App. No.
15/887,838
Granted
Aug 20, 2019
Kind
B2
Abstract

Provided are 4′-O substituted isoindoline compounds, and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed.

Claims (3)

1. A compound having the formula:

or a pharmaceutically acceptable salt, solvate, clathrate, or stereoisomer thereof.

2. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof and one or more excipients.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 30, 2018
From: RUCHELMAN, ALEXANDER L.; MULLER, GEORGE W.; MAN, HON-WAH
To: CELGENE CORPORATION
Reel/Frame 047361/0878 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 30, 2018
From: CHEN, ROGER SHEN-CHU
To: CELGENE CORPORATION
Reel/Frame 047361/0914 →
Continuity (6)
Continuation 14874318 · Oct 2, 2015
Continuation 14083205 · Nov 18, 2013
Division 13410216 · Mar 1, 2012
Continuation 12077715 · Mar 19, 2008
Provisional Application 60919323 · Mar 20, 2007
Related Publication 20180155316A1 · Jun 7, 2018
Cited By (2)
US 12,564,638 US 12,582,641