IP Library › Granted Patent US 10,428,138
Granted Patent B2
US 10,428,138 · App. 16/133,493 · Granted Oct 1, 2019

Antibody and antibody-containing composition

Inventor: Yasuhiro Tsukamoto (Osaka, JP)
Assignees: Ostrich Pharma KK; Immortal Spirit Limited
C07K16/1271C07K16/084C07K16/085C07K16/1045C07K16/1063C07K16/1267C07K2317/11C07K2317/23C07K2317/76C12N2710/14043
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Quick Facts
Patent No.
US 10,428,138
App. No.
16/133,493
Granted
Oct 1, 2019
Kind
B2
Abstract

For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substancesa released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.

Claims (7)

1. A lotion, comprising:

ostrich antibodies which specifically bind to a surface protein of a virus, wherein the virus comprises any one of HPV type 6, 11, 16 or 18; and

water, glycerol, ethanol, sodium polyacrylate, hydroxyethyl cellulose, phenoxyethanol, EDTA-2Na, paraben, polysorbate 80, and fatty acid sorbitan.

2. The lotion of claim 1 , wherein the antibodies are IgY antibodies obtained from an egg of an ostrich immunized with the surface protein as an antigen.

3. The lotion of claim 2 , wherein the virus comprises HPV type 6,11, 16 and 18.

4. The lotion of claim 3 , wherein the surface protein comprises an HPV L1 protein.

5. The lotion of claim 1 , for use in preventing or treating virus infection.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2024
From: IMMORTAL SPIRIT LIMITED
To: ZEAL COSMETICS INC.
Reel/Frame 067214/0842 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 17, 2018
From: TSUKAMOTO, YASUHIRO
To: OSTRICH PHARMA KK; IMMORTAL SPIRIT LIMITED
Reel/Frame 046893/0084 →
Priority Claims (1)
JP 2011-179378 · Aug 19, 2011 · national
Continuity (4)
Continuation 15808807 · Nov 9, 2017
Continuation 15230188 · Aug 5, 2016
Division 14239776
Related Publication 20190016788A1 · Jan 17, 2019
Cited By (1)
US 12,302,685