Apparatus for electrodermal activity measurement with current compensation

1. An apparatus, comprising:

a first electrode configured to be in contact with a first portion of a stratum corneum of skin;

a second electrode configured to be in contact with a second portion of the stratum corneum and in electronic communication with the first electrode through the stratum corneum;

a digital-to-analog converter (DAC) configured to generate a compensation voltage; and

a processor electrically coupled to the first electrode, the second electrode, and the DAC, the processor configured to execute computer-executable instructions to:

(a) bias the first electrode at a first voltage V+ and the second electrode at a second voltage V−;

(b) measure a first current flowing between the first electrode and the second electrode, the first current corresponding to a conductance of the stratum corneum;

(c) subtract a compensation current from the first current to obtain a second current;

(d) amplify the second current and transform the second current to an output voltage;

(e) calculate the conductance of the stratum corneum based on the output voltage, the conductance of the stratum corneum being indicative of an extent of electrodermal activity;

(f) determine whether the output voltage is greater than a threshold value; and

(g) in response to determining that the output voltage is greater than the threshold value, adjust the compensation voltage generated by the DAC to adjust the compensation current subtracted from the first current to prevent saturation of the output voltage.

2. The apparatus of claim 1 , wherein the processor is further configured to execute computer-executable instructions to adjust the compensation voltage to decrease the compensation current if the output voltage falls below a predetermined minimum value.

3. The apparatus of claim 1 , wherein the output voltage is indicative of a phasic value of the electrodermal activity.

4. The apparatus of claim 1 , wherein the processor is further configured to execute computer-executable instructions to reverse a polarity of at least one of the first electrode and the second electrode after a predetermined period of time to reduce electrolysis.

5. The apparatus of claim 1 , wherein the stratum corneum is a stratum corneum of any portion of a person's skin.

6. The apparatus of claim 5 , wherein the conductance of the stratum corneum is a phasic level conductance, the processor further configured to execute the computer-executable instructions to calculate a tonic level conductance of the stratum corneum in the range of 0.05 μS to 50 μS.

7. The apparatus of claim 1 , wherein the processor is configured to execute the computer-executable instructions to calculate the conductance of the stratum corneum with a resolution of 0.0001 μS.

8. The apparatus of claim 1 , further comprising a wrist band including a housing, the processor is disposed in the housing.

9. The apparatus of claim 1 , wherein the apparatus is at least one of a head band, an arm band, a foot band, an ankle band, or a ring.

10. The apparatus of claim 1 , further comprising a heart beat sensor.

11. The apparatus of claim 10 , further comprising at least one of an accelerometer, a temperature sensor, a blood oxygen sensor, and a glucose sensor.

12. The apparatus of claim 11 , further comprising a communications module configured to communicate at least one of heart beat data, an accelerometer data, a temperature data, a blood oxygen data, and a glucose data to an external device.

13. The apparatus of claim 12 , where the communication module is configured to communicate with the external device via at least one of a USB, USB 2.0, IEEE 1394, BLUETOOTH®, low powered BLUETOOTH®, and Wi-Fi.

14. The apparatus of claim 1 , wherein the compensation current is a quasilinear function of the compensation voltage.

15. A method, comprising:

biasing a first electrode at a first voltage V+, the first electrode configured to be in contact with a first portion of a stratum corneum of a user;

biasing a second electrode at a second voltage V−, the second electrode configured to be in contact with a second portion of the stratum corneum and in electronic communication with the first electrode through the stratum corneum;

measuring a first current flowing between the first electrode and the second electrode, the first current corresponding to a conductance of the stratum corneum;

subtracting a compensation current from the first current to obtain a second current;

amplifying the second current and transforming the second current to an output voltage;

calculating the conductance of the stratum corneum based on the output voltage, the conductance of the stratum corneum being indicative of an extent of electrodermal activity;

generating a compensation voltage using a digital-to-analog converter (DAC);

determining whether the output voltage is greater than a threshold value; and

in response to determining that the output voltage is greater than the threshold value, adjusting the compensation voltage generated by the DAC to adjust the compensation current subtracted from the first current to prevent saturation of the output voltage.

16. The method of claim 15 , further comprising reversing a polarity of at least one of the first electrode and the second electrode after a predetermined period of time to reduce electrolysis.

17. The method of claim 15 , wherein the output voltage is indicative of a phasic value of the electrodermal activity.

18. The method of claim 15 , further comprising adjusting the compensation voltage if the output voltage falls below a predetermined minimum value.

19. The method of claim 15 , further comprising generating the compensation current as a quasilinear function of the compensation voltage.