Delivery system
Provided herein is a delivery system, including: (a) an optical sensor configured to detect data to create a map of a patient bodily surface; and (b) a dispenser operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the patient bodily surface based upon the data or map. Methods of forming a tissue on a patient bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing patient bodily surface data.
1. A delivery system for forming skin tissue on a patient bodily surface, said delivery system comprising:
(a) an optical detector configured to detect data to create a map of said patient bodily surface, which optical detector further comprises a depth detector, operatively associated with said optical detector, to account for movement of said patient during said detection, wherein said optical detector comprises a three-dimensional scanner;
(b) a dispenser operatively associated with said optical detector and configured to deliver cells and/or compositions to said patient bodily surface based upon said data or said map;
(c) a three-dimensional plotter operatively connected with said three-dimensional scanner; and
(d) a controller operatively connected with said dispenser.
2. The delivery system of claim 1 , wherein said depth detector comprises an infrared detector.
3. The delivery system of claim 1 , wherein said three-dimensional scanner is a laser scanner.
4. The delivery system of claim 1 , wherein said three-dimensional scanner is a hand-held laser scanner.
5. The delivery system of claim 1 , wherein said dispenser comprises a plurality of nozzles.
6. The delivery system of claim 5 , further comprising one or more cartridges loaded with a composition, said composition optionally comprising cells,
wherein said nozzles are in fluid communication with said one or more cartridges.
7. The delivery system of claim 6 , wherein said nozzles are configured for pressure-based delivery of the compositions.
8. The delivery system of claim 6 , wherein said cells are amniotic fluid stem cells.
9. The delivery system of claim 6 , wherein said cells are skin cells.
10. The delivery system of claim 9 , wherein said cells are autologous.
11. The delivery system of claim 6 , wherein said cells are autologous.
12. The delivery system of claim 8 , wherein said cells are autologous.
13. The delivery system of claim 1 , further comprising:
means for interpreting the data of the patient bodily surface from said optical detector to form a model of the patient bodily surface;
means for transforming said model into a negative mold of the patient bodily surface, which mold is split into a plurality of Z-axis layers, which layers may optionally correspond to one or more tissue layers; and
means for overlaying each of said layers with a series of lines which represent coverage of the patient bodily surface, wherein said lines provide a path for the dispenser.
14. The delivery system of claim 13 , wherein the data of the patient bodily surface is wound surface data.