Delivery system
Provided herein is a delivery system, including: (a) an optical sensor configured to detect data useful to create a map of a bodily surface; and (b) a printer operatively associated with the optical sensor and configured to deliver compositions (optionally including cells) to the bodily surface based upon the data or map. Methods of forming a tissue on a bodily surface of a patient in need thereof are also provided, as are methods, systems and computer program products useful for processing bodily surface data.
1. A delivery system configured to control a three-dimensional optical detector and a printer operatively coupled to the three-dimensional optical detector, the delivery system comprising:
means for interpreting data from the optical detector to form a map of an area of interest of a patient;
means for transforming the map into a negative mold of the area of interest, wherein the mold comprises a plurality of Z-axis layers; and
means for overlaying each of the Z-axis layers of the negative mold with a series of lines, wherein the lines provide a path for control software to use to control the printer to deliver cells and/or compositions to the area of interest in situ based upon the map,
wherein the map is updated in real-time during delivery, by the printer, of the cells and/or compositions.
2. A delivery system comprising:
a three-dimensional optical detector;
a printer operatively coupled to the three-dimensional optical detector; and
a computing system comprising:
a processor; and
a memory coupled to the processor and comprising computer readable program code that when executed by the processor causes the processor to perform operations comprising:
interpreting data from the optical detector to form a map of an area of interest of a patient;
transforming the map into a negative mold of the area of interest, wherein the mold comprises a plurality of Z-axis layers; and
overlaying each of the Z-axis layers of the negative mold with a series of lines, wherein the lines provide a path for control software to use to control the printer to deliver cells and/or compositions to the area of interest in situ based upon the map,
wherein the map is updated in real-time during delivery, by the printer, of the cells and/or compositions.
3. The delivery system of claim 2 , further comprising a surgical device that is configured to provide the optical detector and/or the printer with access to the area of interest of the patient.
4. The delivery system of claim 3 , wherein the surgical device is an endoscopic device.
5. The delivery system of claim 2 , wherein the area of interest comprises an injury or disease of the patient.
6. The delivery system of claim 2 , wherein the data from the optical detector is represented as an object including the Z-axis layers, and
wherein each of the Z-axis layers are represented by a grid that comprises the lines.
7. The delivery system of claim 6 , wherein the operations further comprise directing the printer to deliver cells to a first location of the area of interest that is associated with a first piece of the grid representing the object while analyzing a second piece of the grid.
8. The delivery system of claim 6 , wherein the operations further comprise parsing the object in a manner that incorporates locations of different cells and/or compositions to be printed by the printer.
9. The delivery system of claim 2 , wherein the area of interest is a closed wound.
10. The delivery system of claim 2 , wherein the cells are selected from the group consisting of cartilage cells, bone cells, muscle cells, vascular cells, skin cells, and combinations thereof.
11. The delivery system of claim 2 , wherein the Z-axis layers correspond to one or more tissue layers.
12. A computer program product for processing data of an area of interest of a patient obtained from a three-dimensional optical detector to provide a path to a printer operatively coupled to the three-dimensional optical detector, the computer program product comprising a non-transitory computer readable medium having computer readable program code embodied therein, the computer readable program code comprising:
computer readable program code that interprets data from the optical detector to form a map of the area of interest of the patient;
computer readable program code that transforms the map into a negative mold of the area of interest, wherein the mold comprises a plurality of Z-axis layers; and
computer readable program code that overlays each of the Z-axis layers of the negative mold with a series of lines, wherein the lines provide a path for control software to use to control the printer to deliver cells and/or compositions to the area of interest in situ based upon the map,
wherein the map is updated in real-time during delivery, by the printer, of the cells and/or compositions.
13. The computer program product of claim 12 , wherein the data from the optical detector is represented as an object including the Z-axis layers, and
wherein each of the Z-axis layers are represented by a grid that comprises the lines.
14. The computer program product of claim 11 , wherein the computer readable program code is further configured to direct the printer to deliver cells to a first location of the area of interest that is associated with a first piece of the grid representing the object while analyzing a second piece of the grid.
15. The computer program product of claim 13 , further comprising computer readable program code that parses the object in a manner that incorporates locations of different cells and/or compositions to be printed by the printer.
16. The computer program product of claim 12 , wherein the area of interest is a closed wound.
17. The computer program product of claim 12 , wherein the computer readable program code is further configured to control a surgical device to provide the optical detector and/or the printer with access to the area of interest.
18. The computer program product of claim 17 , wherein the surgical device is an endoscopic device.
19. The computer program product of claim 12 , wherein the area of interest comprises an injury or disease of the patient.
20. The computer program product of claim 12 , wherein the Z-axis layers correspond to one or more tissue layers.