Genetic control of cell size
Described herein are mutant cyanobacterial cell populations that have a smaller mean cell length than wild type cyanobacterial cell populations of the same species.
1. A cyanobacterial population comprising cells with at least one expression cassette comprising a heterologous promoter operably linked to a nucleic acid segment encoding a Cdv3 protein with a sequence comprising at least 95% sequence identity to SEQ ID NO:33.
2. The cyanobacterial population of claim 1 , wherein the promoter is a constitutive promoter, inducible promoter, regulated promoter, cell specific promoter, or synthetic promoter.
3. The cyanobacterial population of claim 1 , wherein the promoter is active before or during log phase growth of the cells in a culture or fermentation medium.
4. The cyanobacterial population of claim 1 , wherein the promoter is active at the end, or after, log phase growth of the cells in a culture or fermentation medium.
5. The cyanobacterial population of claim 1 , wherein the promoter is not a native promoter that would express the Cdv3 protein in a wild type cyanobacteria.
6. The cyanobacterial population of claim 1 , with a mean cell length that is at least 150% greater than a mean cell length of a wild type population of cyanobacteria of the same species.