IP Library › Granted Patent US 10,604,727
Granted Patent B2
US 10,604,727 · App. 16/149,398 · Granted Mar 31, 2020

Bacteria and enzymes produced therefrom and methods of using same

Inventors: Gbenga Ayangbile (Fulton, IL); Mary Grzemski (Fulton, IL); James F. Tobey, Jr. (Fulton, IL); David Spangler (Fulton, IL); Lucas Krueger (Fulton, IL)
Assignee: Agri-King, Inc.
C11D3/38645A23K10/12A23K10/18A23K20/189A23K30/18A23K50/10A23K50/20A23K50/30A23K50/40A23K50/50A23K50/75A61K35/742C02F3/34C12N1/20C12N9/2417C12N9/2437C12P3/00C12P5/023C12R1/125C12Y302/01001C12Y302/01004C02F2103/005Y02E50/343
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Quick Facts
Patent No.
US 10,604,727
App. No.
16/149,398
Granted
Mar 31, 2020
Kind
B2
Abstract

A bacteria referred to here as Bacillus subtilis 6A-1 is provided, compositions thereof and processes for use of the bacteria, spores, cells, extracts and enzymes. The compositions which comprise the bacteria, spores, cells, extracts and/or enzymes are capable of degrading polysaccharides. Such compositions are capable of degrading cellulose, including plant-produced cellulose, microcrystalline cellulose and carboxymethyl cellulose. The bacteria produces at least two cellulose-degrading protein fractions. Cellulose degrading activity continues across pH2 to pH13.

Claims (12)

1. A method of degrading a cellulose comprising at least one polysaccharide, said method comprising combining the cellulose comprising the at least one polysaccharide with a composition comprising:

(a) (i) a Bacillus subtilis 6A-1 (6A-1) reference strain having been deposited at ATCC under deposit number PTA-125135, cells of said 6A-1, or spores produced by said 6A-1;

wherein said 6A-1 strain or cells or spores are filtered, dried, freeze dried or grounded

or

(ii) at least one polysaccharide-degrading enzyme fraction obtained from said 6A-1

and

(b) at least one excipient, carrier or diluent,

wherein said composition degrades said cellulose or the at least one polysaccharide.

2. The method of claim 1 , wherein said composition comprising said 6A-1 strain or said cells or said spores or the at least one polysaccharide-degrading enzyme fraction is capable of degrading crystalline cellulose, carboxymethyl cellulose and unmodified cellulose.

3. The method of claim 1 , wherein said 6A-1 is an asporogenous mutant of said 6A-1.

4. The method of claim 1 , wherein said composition comprising said 6A-1 or said cells or said spores or the at least one polysaccharide-degrading enzyme fraction is capable of degrading cellulose under conditions from pH 2 to pH 13.

5. The method of claim 1 , wherein said method comprises contacting said composition comprising said 6A-1, said cells, said spores or the at least one polysaccharide degrading enzyme fraction with the cellulose, degrading said cellulose under biogas-producing conditions, and collecting said biogas.

Continuity (3)
Continuation 15262989 · Sep 12, 2016
Provisional Application 62218039 · Sep 14, 2015
Related Publication 20190016997A1 · Jan 17, 2019