Systems and methods of cannabis oil extraction
A cannabis oil extraction method includes performing grinding assisted extraction in the presence of solvent, co-solvent extraction with subcritical CO 2 comprising, degassing the CO 2 and separating the mixture by centrifugation.
1. A cannabis oil extraction method, the method comprising:
performing grinding assisted extraction comprising:
grinding plant material in the presence of solvent to generate an extract process material mixture;
performing co-solvent extraction using subcritical CO 2 comprising:
adding liquid CO 2 to the extract process material mixture, and maintaining the extract process material mixture at a temperature and pressure combination sufficient to maintain the liquid CO 2 in a subcritical state;
degassing the CO 2 ; and
separating the extract process material mixture by centrifugation.
2. The method of claim 1 , wherein the plant material ground in the presence of the solvent is wet plant material.
3. The method of claim 1 , wherein a ratio of solvent to plant material present during the grinding assisted extraction is greater than 1:1 on a weight basis.
4. The method of claim 1 , wherein a ratio of solvent to plant material present during the grinding assisted extraction is greater than 2:1 on a weight basis.
5. The method of claim 1 , wherein grinding the plant material in the presence of solvent comprises grinding the plant material to micron scale.
6. The method of claim 5 , wherein the plant material is ground to less than 20 microns during grinding assisted extraction.
7. The method of claim 1 , wherein the solvent is a food grade solvent.
8. The method of claim 1 , wherein the solvent is a non-polar solvent.
9. The method of claim 8 , wherein the non-polar solvent is selected from pentane, hexane, benzene, toluene, carbon tetrachloride, benzene, glycerol monooleate, diethyl ether, hexane, methylene chloride, carbon dioxide, methane, ethylene, D-limonene, olive oil, soybean oil, coconut oil, medium chain triglycerides, methanol, ethanol, propylene glycol, polysorbates 20 and 80 (tween 20 and 80), poloxamer 188, chloroform, diethyl ether, deuterated chloroform, or combination thereof.
10. The method of claim 1 , wherein the solvent is glycerol monooleate.
11. The method of claim 1 , wherein the liquid CO 2 is added to the extract process material mixture at ratio of greater than approximately 1:1 co-solvent to mixture on a weight basis.
12. The method of claim 1 , wherein the extract process material mixture is at a temperature between 30° C. and −18° C. and a pressure of between approximately 5.2 bar and approximately 72 bar when the liquid CO 2 is added to the mixture.
13. The method of claim 1 , further comprising agitating the extract process material mixture during co-solvent extraction with the liquid CO 2 .
14. The method of claim 1 , wherein centrifugation separates the extract process material mixture into a solid phase, oil phase, and water phase.
15. The method of claim 14 , wherein the oil phase comprises extract extracted from the plant material, and wherein the method further comprises:
winterizing the extract in an inline winterization unit;
filtering the winterized extract with a micron filter;
preheating the filtered extract with a preheater;
evaporating a first portion of the extract in an evaporation chamber of a short-path distillation unit, wherein a second portion of the extract passes through the evaporation chamber without evaporating;
condensing the first portion of the extract in a vertical condenser; and
evaporating one or more additional portions of the second portion of the extract in the same or one or more additional evaporation chambers at higher temperatures and condensing these one or more portions separately in the same or one or more additional vertical condensers to obtain refined cannabis oil pay product comprising cannabinoids isolated by weight.
16. The method of claim 1 , wherein degassing the CO 2 comprises heating the extract process material mixture before or during centrifugation.
17. The method of claim 1 , wherein at least a portion of the CO 2 is degassed during centrifugation.
18. The method of claim 1 , wherein degassing the CO 2 comprises allowing a supernatant component of the separated extract process material mixture generated by the centrifugation to expand.
19. The method of claim 1 , further comprising heating the extract process material mixture after the co-solvent extraction to drive degassing of the liquid CO 2 co-solvent.
20. The method of claim 19 , wherein heating the extract process material mixture after the co-solvent extraction comprises heating the mixture to between 26° C. and 32° C.
21. The method of claim 1 , wherein the solvent comprises a polar solvent and a non-polar solvent.