Devices and methods and agent-assisted medical procedures
Various embodiments of bulking or cushioning agents or material and related medical devices and methods are disclosed. For example, a method of performing a medical procedure in a tract of a body may include injecting a material in a liquid phase proximate a target site between a first tissue layer and a second tissue layer, allowing the material to transition from the liquid phase to the gel phase in response to a raise in temperature of the material to approximately at or above the predetermined temperature, and performing a surgical procedure on the target site. The material may have the liquid phase at temperatures below a predetermined temperature and a gel phase at temperature approximately at or above the predetermined temperature.
1. A method of performing a medical procedure, comprising:
injecting a material at a target site under a tissue surface, the material transitioning from a first viscosity to a second viscosity upon injection, the second viscosity being greater than the first viscosity; and
performing the medical procedure on the target site;
wherein the medical procedure includes a tissue resection, wherein the medical procedure includes a tissue dissection, or wherein tissue defining the tissue surface includes at least one of mucosal tissue and submucosal tissue.
2. The method of claim 1 , wherein the medical procedure includes the tissue resection and wherein the medical procedure includes removing tissue from the target site.
3. The method of claim 1 , wherein the medical procedure includes the tissue resection or the tissue dissection.
4. The method of claim 1 , wherein the tissue defining the tissue surface includes at least one of mucosal tissue and submucosal tissue.
5. The method of claim 1 , wherein the tissue resection or the tissue dissection is an endoscopic mucosal resection or an endoscopic submucosal dissection.
6. The method of claim 1 , wherein the material includes a therapeutic agent.
7. The method of claim 1 , wherein the material includes an imaging agent.
8. A method of performing a medical procedure, comprising:
injecting a material at a target site under a tissue surface, wherein injecting the material causes the tissue surface to protrude, the material transitioning from a first viscosity to a second viscosity upon injection, the second viscosity being greater than the first viscosity; and
performing the medical procedure on the protruded tissue surface;
wherein the medical procedure includes a tissue resection, wherein the medical procedure includes a tissue dissection, or wherein tissue defining the tissue surface includes at least one of mucosal tissue and submucosal tissue.
9. The method of claim 8 , wherein the medical procedure includes the tissue resection and wherein the medical procedure includes removing tissue from the target site.
10. The method of claim 8 , wherein the medical procedure includes the tissue resection or the tissue dissection.
11. The method of claim 8 , wherein the tissue defining the tissue surface includes at least one of mucosal tissue and submucosal tissue.
12. The method of claim 8 , wherein the tissue resection or the tissue dissection is an endoscopic mucosal resection or an endoscopic submucosal dissection.
13. The method of claim 8 , wherein the material includes a therapeutic agent.
14. The method of claim 8 , wherein the material includes an imaging agent.
15. A method of performing a medical procedure, comprising:
injecting a material at a target site under a tissue surface defining a tract, wherein injecting the material causes the tissue surface to protrude, the material transitioning from a first viscosity to a second viscosity upon injection, the second viscosity being greater than the first viscosity; and
performing the medical procedure at the target site;
wherein the medical procedure includes a tissue resection, wherein the medical procedure includes a tissue dissection, or wherein tissue defining the tissue surface includes at least one of mucosal tissue and submucosal tissue.
16. The method of claim 15 , wherein the tract is a GI tract.
17. The method of claim 15 , wherein the medical procedure includes the tissue resection and wherein the medical procedure includes removing tissue from the target site.
18. The method of claim 15 , wherein the medical procedure includes the tissue resection or the tissue dissection.
19. The method of claim 15 , wherein the tissue defining the tissue surface includes at least one of mucosal tissue and submucosal tissue.
20. The method of claim 15 , the tissue resection or the tissue dissection is an endoscopic mucosal resection or an endoscopic submucosal dissection.