Patent
The present invention relates to Bacillus strains which improves health and performance of production animals. The invention further relates to compositions comprising the Bacillus strains.
1. A composition comprising a carrier, a flowability agent comprising sodium aluminium silicate and/or colloidal amorphous silica, and spores of a Bacillus strain characterized in having deposit accession number DSM 29870 or a mutant strain thereof having all of the identifying characteristics of Bacillus DSM 29870;
wherein the Bacillus strain is sensitive to at least seven of the antibiotics selected from the group consisting of Vancomycin, Clindamycin, Chloramphenicol, Gentamicin, Kanamycin, Streptomycin, Erythromycin and Tetracycline; and wherein the Bacillus strain is non-hemolytic.
2. The composition according to claim 1 , wherein the Bacillus spores of the composition are present as dried spores.
3. The composition according to claim 2 , wherein the composition has a bacterial count of each Bacillus spore between 1×10 4 and 1×10 18 CFU/kg of composition.
4. The composition according to claim 1 , wherein the carrier comprises one or more of the following compounds: water, glycerol, ethylene glycol, 1, 2-propylene glycol or 1, 3-propylene glycol, sodium chloride, sodium benzoate, potassium sorbate, sodium sulfate, potassium sulfate, magnesium sulfate, sodium thiosulfate, calcium carbonate, sodium citrate, dextrin, maltodextrin, glucose, sucrose, sorbitol, lactose, wheat flour, wheat bran, corn gluten meal, starch, farigel, cassava cores, Sipernat 50S, polyethylene glycol 200, polyethylene glycol 400, polyethylene glycol 600, polyethylene glycol 1000, polyethylene glycol 1500, polyethylene glycol 4000, carbopol, and cellulose.
5. The composition according to claim 1 , wherein the carrier comprises calcium carbonate.
6. The composition according to claim 1 , further comprising one or more components selected from the list consisting of: one or more enzymes, one or more additional microbes, one or more vitamins, one or more minerals, one or more amino acids, and one or more other feed ingredients.
7. A composition comprising a carrier, a flowability agent comprising sodium aluminium silicate and/or colloidal amorphous silica, and spores of a Bacillus strain characterized in having deposit accession number DSM 29869 or a mutant strain thereof having all of the identifying characteristics of Bacillus DSM 29869,
wherein the Bacillus strain is sensitive to at least seven of the antibiotics selected from the group consisting of Vancomycin, Clindamycin, Chloramphenicol, Gentamicin, Kanamycin, Streptomycin, Erythromycin and Tetracycline; and wherein the Bacillus strain is non-hemolytic.
8. The composition according to claim 7 , wherein the Bacillus spores of the composition are present as dried spores.
9. The composition according to claim 8 , wherein the composition has a bacterial count of each Bacillus spore between 1×10 4 and 1×10 18 CFU/kg of composition.
10. The composition according to claim 7 , wherein the carrier comprises one or more of the following compounds: water, glycerol, ethylene glycol, 1, 2-propylene glycol or 1, 3-propylene glycol, sodium chloride, sodium benzoate, potassium sorbate, sodium sulfate, potassium sulfate, magnesium sulfate, sodium thiosulfate, calcium carbonate, sodium citrate, dextrin, maltodextrin, glucose, sucrose, sorbitol, lactose, wheat flour, wheat bran, corn gluten meal, starch, farigel, cassava cores, Sipernat 50S, polyethylene glycol 200, polyethylene glycol 400, polyethylene glycol 600, polyethylene glycol 1000, polyethylene glycol 1500, polyethylene glycol 4000, carbopol, and cellulose.
11. The composition according to claim 7 , further comprising one or more components selected from the list consisting of: one or more enzymes, one or more additional microbes, one or more vitamins, one or more minerals, one or more amino acids, and one or more other feed ingredients.
12. A composition comprising a carrier, a flowability agent comprising sodium aluminium silicate and/or colloidal amorphous silica, and spores of a Bacillus strain characterized in having deposit accession number DSM 29871 or a mutant strain thereof having all of the identifying characteristics of Bacillus DSM 29871,
wherein the Bacillus strain is sensitive to at least seven of the antibiotics selected from the group consisting of Vancomycin, Clindamycin, Chloramphenicol, Gentamicin, Kanamycin, Streptomycin, Erythromycin and Tetracycline; and wherein the Bacillus strain is non-hemolytic.
13. The composition according to claim 12 , wherein the Bacillus spores of the composition are present as dried spores.
14. The composition according to claim 13 , wherein the composition has a bacterial count of each Bacillus spore between 1×10 4 and 1×10 18 CFU/kg of composition.
15. The composition according to claim 12 , wherein the carrier comprises one or more of the following compounds: water, glycerol, ethylene glycol, 1, 2-propylene glycol or 1, 3-propylene glycol, sodium chloride, sodium benzoate, potassium sorbate, sodium sulfate, potassium sulfate, magnesium sulfate, sodium thiosulfate, calcium carbonate, sodium citrate, dextrin, maltodextrin, glucose, sucrose, sorbitol, lactose, wheat flour, wheat bran, corn gluten meal, starch, farigel, cassava cores, Sipernat 50S, polyethylene glycol 200, polyethylene glycol 400, polyethylene glycol 600, polyethylene glycol 1000, polyethylene glycol 1500, polyethylene glycol 4000, carbopol, and cellulose.
16. The composition according to claim 12 , further comprising one or more components selected from the list consisting of: one or more enzymes, one or more additional microbes, one or more vitamins, one or more minerals, one or more amino acids, and one or more other feed ingredients.
17. A composition comprising a carrier, a flowability agent comprising sodium aluminium silicate and/or colloidal amorphous silica, and spores of a Bacillus strain characterized in having deposit accession number DSM 29872 or a mutant strain thereof having all of the identifying characteristics of Bacillus DSM 29872,
wherein the Bacillus strain is sensitive to at least seven of the antibiotics selected from the group consisting of Vancomycin, Clindamycin, Chloramphenicol, Gentamicin, Kanamycin, Streptomycin, Erythromycin and Tetracycline; and wherein the Bacillus strain is non-hemolytic.
18. The composition according to claim 17 , wherein the Bacillus spores of the composition are present as dried spores.
19. The composition according to claim 17 , wherein the composition has a bacterial count of each Bacillus spore between 1×10 4 and 1×10 18 CFU/kg of composition.
20. The composition according to claim 17 , wherein the carrier comprises one or more of the following compounds: water, glycerol, ethylene glycol, 1, 2-propylene glycol or 1, 3-propylene glycol, sodium chloride, sodium benzoate, potassium sorbate, sodium sulfate, potassium sulfate, magnesium sulfate, sodium thiosulfate, calcium carbonate, sodium citrate, dextrin, maltodextrin, glucose, sucrose, sorbitol, lactose, wheat flour, wheat bran, corn gluten meal, starch, farigel, cassava cores, Sipernat 50S, polyethylene glycol 200, polyethylene glycol 400, polyethylene glycol 600, polyethylene glycol 1000, polyethylene glycol 1500, polyethylene glycol 4000, carbopol, and cellulose.
21. The composition according to claim 17 , further comprising one or more components selected from the list consisting of: one or more enzymes, one or more additional microbes, one or more vitamins, one or more minerals, one or more amino acids, and one or more other feed ingredients.