Photoprotective compositions containing

1. A compound having the structure of the following formula:

wherein:

X is selected from the group consisting of NR 14 and O;

Y is CR 5 R 6 , O, or NR 15 ;

R 1 , R 2 , R 3 , R 4 , R 7 , R 8 , R 9 , R 10 , and R 11 are independently selected from the group consisting of hydrogen, halogen, CN, hydroxyl, R 16 , and OR 16 ,

R 13 is hydrogen,

R 14 and R 15 are independently hydrogen or R 16 ;

R 5 and R 6 are independently selected from the group consisting of hydrogen, hydroxyl, OR 16 , R 16 , and C 3-6 cycloalkyl, or R 5 and R 6 combine to form an oxo (═O) group or a C 3-6 cycloalkyl;

R 12 is COR a ;

each R 16 is independently formyl, C 1-9 alkyl, C 2-9 alkenyl, or C 2-9 alkynyl; and,

R a is selected from the group consisting of hydrogen, hydroxyl, and OR 16 ;

wherein:

if R a is hydrogen, Y is CR 5 R 6 , and R 14 is hydrogen, then

R 5 is selected from the group consisting of hydroxyl, OR 16 , and C 3-6 cycloalkyl, or R 5 and R 6 combine to form a C 3-6 cycloalkyl;

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

2. The compound of claim 1 , having the following structure:

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

3. A compound having the structure of the following formula:

wherein:

X is selected from the group consisting of NR 14 and O;

R 1 , R 2 , R 3 , R 4 , R 7 , R 8 , R 9 , R 10 , and R 11 are independently selected from the group consisting of hydrogen, halogen, CN, hydroxyl, R 16 , and OR 16 ,

R 13 is hydrogen,

R 14 is hydrogen or R 16 ;

R 12 is COR a ;

each R 16 is independently formyl, C 1-9 alkyl, C 2-9 alkenyl, or C 2-9 alkynyl;

R a is selected from the group consisting of hydrogen, hydroxyl, and OR 16 ;

Y is CR 5 R 6 ;

R 5 is hydrogen, and R 6 is C 3-6 cycloalkyl, or O—(C 1-4 alkyl);

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

4. The compound of claim 1 , wherein each of R 1 , R 2 , R 3 , R 4 , R 7 , R 8 , R 9 , R 10 , and R 11 is hydrogen,

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

5. The compound of claim 3 ,

wherein:

X is NH;

each of R 1 , R 3 , R4, R 7 , R 8 , R 9 , R 10 , and R 11 is hydrogen; and

R 2 is hydrogen or C 1-4 alkyl;

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

6. The compound according to claim 1 , wherein the compound is:

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

7. A composition comprising a compound, the compound having the structure of the following formula:

wherein:

X is selected from the group consisting of NR 14 and O;

Y is CR 5 R 6 , O, or NR 15 ;

R 1 , R 2 , R 3 , R 4 , R 7 , R 8 , R 9 , R 10 , and R 11 are independently selected from the group consisting of hydrogen, halogen, CN, hydroxyl, R 16 , and OR 16 ;

R 13 is hydrogen,

R 14 and R 15 are independently hydrogen or R 16 ;

R 5 and R 6 are independently selected from the group consisting of hydrogen, hydroxyl, OR 16 , R 16 , and C 3-6 cycloalkyl, or R 5 and R 6 combine to form an oxo (═O) group or a C 3-6 cycloalkyl;

R 12 is COR a ;

each R 16 is independently formyl, C 1-9 alkyl, C 2-9 alkenyl, or C 2-9 alkynyl; and,

R a is selected from the group consisting of hydrogen, hydroxyl, and OR 16 ;

wherein:

if R a is hydrogen, Y is CR 5 R 6 , and R 14 is hydrogen, then

R 5 is selected from the group consisting of hydroxyl, OR 16 , and C 3-6 cycloalkyl, or R 5 and R 6 combine to form a C 3-6 cycloalkyl;

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

8. The composition of claim 7 , wherein the composition comprises a compound having the following structure:

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

9. A composition comprising a compound, the compound having the structure of the following formula:

wherein:

X is selected from the group consisting of NR 14 and O;

R 1 , R 2 , R 3 , R 4 , R 7 , R 8 , R 9 , R 10 , and R 11 are independently selected from the group consisting of hydrogen, halogen, CN, hydroxyl, R 16 , and OR 16 ,

R 13 is hydrogen,

R 14 is hydrogen or R 16 ;

R 12 is COR a ;

each R 16 is independently formyl, C 1-9 alkyl, C 2-9 alkenyl, or C 2-9 alkynyl;

R a is selected from the group consisting of hydrogen, hydroxyl, and OR 16 ;

Y is CR 5 R 6 ;

R 5 is hydrogen, and R 6 is C 3-6 cycloalkyl, or O—(C 1-4 alkyl);

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

10. The composition of claim 7 , wherein each of R 1 , R 2 , R 3 , R 4 , R 7 , R 8 , R 9 , R 10 , and R 11 is hydrogen.

11. The composition of claim 9 ,

wherein:

is NH;

each of R 1 , R 3 , R 4 , R 7 , R 8 , R 9 , R 10 , and R 11 is hydrogen; and

R 2 is hydrogen or C 1-4 alkyl.

12. A composition according to claim 7 , wherein the compound is:

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

13. The compound of claim 1 , wherein X is NH;

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

14. The compound of claim 2 , wherein X is NH;

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

15. The compound of claim 3 , wherein X is NH;

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

16. The compound of claim 4 , wherein X is NH;

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

17. The compound of claim 5 , wherein R 12 is CO(—O—C 1-4 alkyl);

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

18. The compound of claim 13 , wherein R 12 is CO(—O—C 1-4 alkyl);

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

19. The compound of claim 14 , wherein R 12 is CO(—O—C 1-4 alkyl);

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

20. The compound of claim 15 , wherein R 12 is CO(—O—C 1-4 alkyl);

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

21. The compound of claim 16 , wherein R 12 is CO(—O—C 1-4 alkyl);

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

22. The compound of claim 5 , wherein Y is CH(C 3 H 5 );

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

23. The compound of claim 17 , wherein Y is CH(C 3 H 5 );

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

24. The compound of claim 18 , wherein Y is CH(C 3 H 5 );

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

25. The compound of claim 19 , wherein Y is CH(C 3 H 5 );

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

26. The compound of claim 20 , wherein Y is CH(C 3 H 5 );

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

27. The compound of claim 21 , wherein Y is CH(C 3 H 5 );

or a hydrate or cosmetically or pharmaceutically acceptable salt thereof.

28. The composition of claim 7 , wherein X is NH.

29. The composition of claim 8 , wherein X is NH.

30. The composition of claim 9 , wherein X is NH.

31. The composition of claim 10 , wherein X is NH.

32. The composition of claim 11 , wherein R 12 is CO(—O—C 1-4 alkyl).

33. The composition of claim 28 , wherein R 12 is CO(—O—C 1-4 alkyl).

34. The composition of claim 29 , wherein R 12 is CO(—O—C 1-4 alkyl).

35. The composition of claim 30 , wherein R 12 is CO(—O—C 1-4 alkyl).

36. The composition of claim 31 , wherein R 12 is CO(—O—C 1-4 alkyl).

37. The composition of claim 11 , wherein Y is CH(C 3 H 5 ).

38. The composition of claim 32 , wherein Y is CH(C 3 H 5 ).

39. The composition of claim 33 , wherein Y is CH(C 3 H 5 ).

40. The composition of claim 34 , wherein Y is CH(C 3 H 5 ).

41. The composition of claim 35 , wherein Y is CH(C 3 H 5 ).

42. The composition of claim 36 , wherein Y is CH(C 3 H 5 ).