IP Library Granted Patent US 11,246,697
Granted Patent B2
US 11,246,697 · App. 16/410,167 · Granted Feb 15, 2022

Method and apparatus for creating a reconstructive graft

Inventor: Barry Markman (Las Vegas, NV)
Assignee: Markman Biologics Corporation
A61F2/0077A61F2/0063A61F2/02A61L27/3604A61L27/3683A61L27/54A61F2/0059A61F2/12A61F2002/0068A61F2002/0081A61F2230/0067A61F2240/002A61F2240/005A61F2250/0026A61F2250/0048A61F2250/0051A61F2250/0067A61F2250/0068
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Quick Facts
Patent No.
US 11,246,697
App. No.
16/410,167
Granted
Feb 15, 2022
Kind
B2
Abstract

A method and apparatus is provided for creating an internal reconstruction tissue graft. Templates may be used to create a multitude of patterns in a variety of tissue reconstruction grafts. An apparatus may be used to create an internal tissue graft for reconstruction through either compression and/or removal of segments. An apparatus may be used, through either compression and or removal of segments of a preformed template made of synthetics and or metal that mirrors a template that can be used as an internal tissue graft for reconstruction. In a method, such as using software analysis and an apparatus, the physical properties of the tissue graft and its pre- and post-operative properties and appearance may be measured.

Claims (20)

1. A method of creating a modified tissue graft for implantation at an anatomical site of a human body, comprising the steps of:

(a) obtaining a tissue graft from a location different than said anatomical site, said tissue graft having an exterior surface;

(b) identifying said anatomical site at which said modified tissue graft is to be placed; and

(c) using at least one template to modify at least a portion of said exterior surface of said tissue graft by cutting and/or removing one or more portions of said exterior surface of said tissue graft with said at least one template, whereby said portion of said exterior surface comprises an area of said tissue graft having increased expandability, traction or adhesion, as compared to said exterior surface of said tissue graft without modification.

2. The method in accordance with claim 1 , wherein said modified tissue graft is an external tissue graft.

3. The method in accordance with claim 1 , wherein said step of cutting and/or removing creates one or more openings in said tissue graft and further comprising associating one or more medicants with one or more of said openings.

4. The method in accordance with claim 3 , wherein said one or more medicants comprise at least one of: an antibiotic, a growth factor, and a chemotherapeutic.

5. The method in accordance with claim 1 , wherein said portion is located at a first side of said tissue graft.

6. The method in accordance with claim 1 , comprising pressing said template into said exterior surface of said tissue graft.

7. The method in accordance with claim 1 , wherein said cutting creates a plurality of spaced incisions, increasing said expandability of said tissue graft at said portion.

8. A modified tissue graft for implantation at an anatomical site of a human body, said modified tissue graft including one or more areas of increased expandability, traction or adhesion, prepared by the process of:

(a) obtaining a tissue graft from a location different than said anatomical site, said tissue graft having an exterior surface;

(b) identifying said anatomical site at which said modified tissue graft is to be placed; and

(c) using at least one template to modify at least a portion of said exterior surface of said tissue graft by cutting and/or removing one or more portions of said exterior surface of said tissue graft with said at least one template, whereby said portion of said exterior surface comprises said area of said tissue graft having increased expandability, traction or adhesion, as compared to said exterior surface of said tissue graft without modification.

9. The modified tissue graft in accordance with claim 8 , wherein said modified tissue graft is an external tissue graft.

10. The modified tissue graft in accordance with claim 8 , wherein said step of cutting and/or removing creates one or more openings in said tissue graft and further comprising associating one or more medicants with one or more of said openings.

11. The modified tissue graft in accordance with claim 10 , wherein said one or more medicants comprise at least one of: an antibiotic, a growth factor, and a chemotherapeutic.

12. The modified tissue graft in accordance with claim 8 , wherein said portion is located at a first side of said tissue graft.

13. The modified tissue graft in accordance with claim 8 , comprising pressing said template into said exterior surface of said tissue graft.

14. The modified tissue graft in accordance with claim 8 , wherein said cutting creates a plurality of spaced incisions, increasing said expandability of said tissue graft at said portion.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF APPLICANT PREVIOUSLY RECORDED ON REEL 67051 FRAME 308. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jul 16, 2025
From: MARKMAN BIOLOGICS CORPORATION
To: CELLTHERX CORP
Reel/Frame 072050/0092 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 9, 2024
From: MARKMAN BIOLOGICS CORPORATION
To: CELLTHERX
Reel/Frame 067051/0308 →
RELEASE OF SECURITY INTEREST Recorded Apr 8, 2024
From: MARKMAN, BARRY
To: MARKMAN BIOLOGICS CORPORATION
Reel/Frame 067032/0745 →
SECURITY INTEREST Recorded Aug 28, 2020
From: MARKMAN BIOLOGICS CORPORATION
To: MARKMAN, BARRY
Reel/Frame 053627/0532 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 26, 2019
From: MARKMAN, BARRY
To: MARKMAN BIOLOGICS CORPORATION
Reel/Frame 050162/0617 →
Continuity (6)
Continuation 15487585 · Apr 14, 2017
Continuation 14678188 · Apr 3, 2015
Continuation In Part 13687082 · Nov 28, 2012
Continuation 13101022 · May 4, 2011
Provisional Application 61331805 · May 5, 2010
Related Publication 20190262116A1 · Aug 29, 2019
Cited By (3)
US 1,101,168 US 12,458,730 US 12,496,179