IP Library Granted Patent US 11,298,262
Granted Patent B2
US 11,298,262 · App. 16/516,356 · Granted Apr 12, 2022

Ophthalmic device for drug delivery

Inventors: Malik Y. Kahook (Denver, CO); Glenn Sussman (Aliso Viejo, CA); Craig Alan Cable, II (Aliso Viejo, CA)
Assignees: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE; SPYGLASS PHARMA, INC.
A61F9/0017A61F2/147A61F2/15A61F2/16A61F2002/169A61F2002/1683A61F2002/1689A61F2002/1699A61F2002/16905A61F2220/0033A61F2230/0065A61F2250/0063A61F2250/0067
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Quick Facts
Patent No.
US 11,298,262
App. No.
16/516,356
Granted
Apr 12, 2022
Kind
B2
Abstract

An ophthalmic implant for drug delivery. The implant includes a primary intracapsular device coupled to a secondary device, wherein, when implanted in a patient's eye, the primary intracapsular device is held in place by the patient's capsular bag and the secondary device is held in place by the primary intracapsular device. The implant may be inserted in the eye by injecting the primary intracapsular device into the eye either before or after attaching the secondary device to the primary intracapsular device, and subsequently positioning the joined secondary device and primary intracapsular device with the primary intracapsular device held in place by the patient's capsular bag and the secondary device held in place by the primary intracapsular device. The secondary device may be designed to hold a tertiary device that can be implanted and attached at the time of surgery or anytime postoperatively.

Claims (21)

1. An ophthalmic implant comprising:

a multi-part IOL assembly comprising a primary device ( 23 ) comprising an IOL ( 22 ) and a secondary device comprising a first drug delivery device ( 30 );

wherein:

said IOL ( 22 ) comprising a lens ( 24 ), a tab ( 26 ), and a haptic ( 28 );

said tab ( 26 ) extending from the IOL ( 22 ), and said tab ( 26 ) configured to engage the first drug delivery device ( 30 );

said haptic ( 28 ) extending radially outwardly from the lens ( 24 ), such that said haptic ( 28 ) is configured to hold the IOL ( 22 ) in place within a capsular bag of a patient's eye;

said first drug delivery device ( 30 ) comprises a ring configured for a mechanical fit on the tab ( 26 ); and

in an assembled configuration, the first drug delivery device ( 30 ) is engaged in said mechanical fit with the tab ( 26 ) to secure the first drug delivery device ( 30 ) to the IOL ( 22 ) such that the tab ( 26 ) extends from the IOL ( 22 ) through a hole in the first drug delivery device ( 30 ) to establish said mechanical fit on the tab ( 26 ).

2. The ophthalmic implant of claim 1 , wherein:

the first drug delivery device ( 30 ) comprises a drug pad integrated into the first drug delivery device ( 30 ).

3. The ophthalmic implant of claim 1 , wherein:

the first drug delivery device ( 30 ) is further configured to comprise a drug pad.

4. The ophthalmic implant of claim 1 , wherein:

the first drug delivery device ( 30 ) further comprises a refillable reservoir.

5. The ophthalmic implant of claim 1 , further comprising:

a second drug delivery device ( 39 ) configured for attachment to the first drug delivery device ( 30 ).

6. The ophthalmic implant of claim 1 , wherein:

the haptic ( 28 ) extending radially outwardly from the lens ( 24 ) extends outwardly in a plane of the lens.

7. The ophthalmic implant of claim 1 , wherein:

the IOL ( 22 ) has an anterior side ( 24 ) and is configured for placement into the eye of a patient with said anterior side ( 24 ) disposed anteriorly in the eye of the patient; and

the tab ( 26 ) extends from the anterior side ( 24 ) of the IOL ( 22 ).

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 30, 2022
From: KAHOOK, MALIK Y.; SUSSMAN, GLENN
To: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
Reel/Frame 061930/0417 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 30, 2022
From: CABLE, CRAIG ALAN, II
To: SPYGLASS PHARMA, INC.
Reel/Frame 061930/0454 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 28, 2021
From: SUSSMAN, GLENN; CABLE, CRAIG ALAN, II
To: SPYGLASS OPHTHALMICS, INC.
Reel/Frame 057952/0578 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 27, 2021
From: KAHOOK, MALIK Y.
To: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
Reel/Frame 057929/0910 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 27, 2021
From: SUSSMAN, GLENN; CALBE, CRIAG ALAN, II
To: SPYGLASS OPHTHALMICS, INC.
Reel/Frame 057929/0592 →
CHANGE OF NAME Recorded Oct 27, 2021
From: SPYGLASS OPHTHALMICS, INC.
To: SPYGLASS PHARMA, INC.
Reel/Frame 057940/0150 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2020
From: KAHOOK, MALIK Y.; SUSSMAN, GLENN; CABLE, CRAIG ALAN, II
To: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
Reel/Frame 052261/0937 →
Continuity (4)
Provisional Application 62820381 · Mar 19, 2019
Provisional Application 62719922 · Aug 20, 2018
Provisional Application 62702169 · Jul 23, 2018
Related Publication 20200022840A1 · Jan 23, 2020
Cited By (12)
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