Heat exchanger and oxygenator

1. A heat exchanger for a blood circulation circuit, comprising:

a hollow fiber membrane layer having a plurality of hollow fiber membranes; and

a housing receiving the hollow fiber membrane layer to define a first flow path including hollow portions of the hollow fiber membranes and to define a second flow path in a gap between the hollow fiber membranes, wherein one of the flow paths conveys blood and the other flow path conveys a heat medium;

wherein each of the hollow fiber membranes is comprised of a plurality of laminated layers including a barrier layer having a hydrogen peroxide barrier property; and

wherein the barrier layer has an oxygen permeability coefficient of 6 cc·cm/m 2 ·24 h/atm or less at 25° C.

2. The heat exchanger according to claim 1 :

wherein the barrier layer is comprised of a crystalline resin material.

3. The heat exchanger according to claim 2 :

wherein the crystalline resin material includes an aliphatic polyamide.

4. The heat exchanger according to claim 3 :

wherein the aliphatic polyamide is comprised of at least one of polyamide 11, polyamide 12, polyamide 10-10, and polyamide 10-12.

5. The heat exchanger according to claim 3 :

wherein the number of carbon atoms in amide groups of a molecule of the aliphatic polyamide is N, and wherein the number of carbon atoms in methylene groups of the aliphatic polyamide is n; and

wherein n/N is 9 or larger.

6. The heat exchanger according to claim 2 :

wherein the plurality of layers further includes a heat conductive layer having a thermal conductivity higher than a thermal conductivity of the barrier layer.

7. The heat exchanger according to claim 6 :

wherein the heat conductive layer has a thermal conductivity between 0.2 W/m·K and 0.60 W/m·K.

8. The heat exchanger according to claim 1 :

wherein the hollow fiber membrane layer has a shape of a cylindrical body and has the hollow fiber membranes wound around a central axis of the cylindrical body and inclined with respect to the central axis of the cylindrical body.

9. The heat exchanger according to claim 1 :

wherein the hollow fiber membrane layer includes a formed sheet material having the plurality of hollow fiber membranes braided.

10. The heat exchanger according to claim 1 :

wherein the heat medium is comprised of a hydrogen peroxide solution which is circulated through the first flow path, and wherein the blood is circulated through the second flow path.

11. A heat exchanger for a blood circulation circuit, comprising:

a hollow fiber membrane layer having a plurality of hollow fiber membranes; and

a housing receiving the hollow fiber membrane layer to define a first flow path including hollow portions of the hollow fiber membranes and to define a second flow path in a gap between the hollow fiber membranes, wherein one of the flow paths conveys blood and the other flow path conveys a heat medium;

wherein the hollow fiber membranes are comprised of a plurality of laminated layers in a thickness direction of the hollow fiber membranes; and

wherein one of the layers is a barrier layer having a hydrogen peroxide barrier property with an oxygen permeability coefficient of 6 cc·cm/m 2 ·24 h/atm or less at 25° C.

12. An oxygenator for a blood circulation circuit, comprising:

a hollow fiber membrane layer having a plurality of hollow fiber membranes; and

a housing receiving the hollow fiber membrane layer to define a first flow path including hollow portions of the hollow fiber membranes and to define a second flow path in a gap between the hollow fiber membranes, wherein one of the flow paths conveys blood and the other flow path conveys a heat medium;

wherein each of the hollow fiber membranes is comprised of a plurality of laminated layers including a barrier layer having a hydrogen peroxide barrier property; and

wherein the barrier layer has an oxygen permeability coefficient of 6 cc·cm/m 2 ·24 h/atm or less at 25° C.

13. The oxygenator according to claim 12 :

wherein the barrier layer is comprised of a crystalline resin material.

14. The oxygenator according to claim 13 :

wherein the crystalline resin material includes an aliphatic polyamide.

15. The oxygenator according to claim 14 :

wherein the aliphatic polyamide is comprised of at least one of polyamide 11, polyamide 12, polyamide 10-10, and polyamide 10-12.

16. The oxygenator according to claim 14 :

wherein the number of carbon atoms in amide groups of a molecule of the aliphatic polyamide is N, and wherein the number of carbon atoms in methylene groups of the aliphatic polyamide is n; and

wherein n/N is 9 or larger.

17. The oxygenator according to claim 13 :

wherein the plurality of layers further includes a heat conductive layer having a thermal conductivity higher than a thermal conductivity of the barrier layer.

18. The oxygenator according to claim 17 :

wherein the heat conductive layer has a thermal conductivity between 0.2 W/m·K and 0.60 W/m·K.

19. The oxygenator according to claim 12 :

wherein the hollow fiber membrane layer has a shape of a cylindrical body and has the hollow fiber membranes wound around a central axis of the cylindrical body and inclined with respect to the central axis of the cylindrical body.

20. The oxygenator according to claim 12 :

wherein the hollow fiber membrane layer includes a formed sheet material having the plurality of hollow fiber membranes braided.