IP Library › Granted Patent US 11,939,329
Granted Patent B2
US 11,939,329 · App. 18/099,770 · Granted Mar 26, 2024

PARP1 inhibitors and uses thereof

Inventors: Robert L. Hoffman (San Diego, CA); Porino Jinjo Va (San Diego, CA); Joseph Robert Pinchman (San Diego, CA); Lynnie Trzoss (San Diego, CA); Qing Dong (San Diego, CA); Stephen W. Kaldor (Foster City, CA)
Assignee: XinThera, Inc.
C07D471/04C07D401/12C07B2200/05
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Quick Facts
Patent No.
US 11,939,329
App. No.
18/099,770
Granted
Mar 26, 2024
Kind
B2
Abstract

Described herein are PARP1 inhibitors and pharmaceutical compositions comprising said inhibitors. The subject compounds and compositions are useful for the treatment of cancer.

Claims (9)

1. A compound selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.

3. The compound of claim 1 that is

or a pharmaceutically acceptable salt thereof.

4. The compound of claim 1 that is

or a pharmaceutically acceptable salt thereof.

5. The compound of claim 1 that is

or a pharmaceutically acceptable salt thereof.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 30, 2023
From: HOFFMAN, ROBERT L.; VA, PORINO JINJO; PINCHMAN, JOSEPH ROBERT; TRZOSS, LYNNIE; DONG, QING
To: XINTHERA, INC.
Reel/Frame 062526/0715 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 30, 2023
From: KALDOR, STEPHEN W.
To: XINTHERA, INC.
Reel/Frame 062526/0764 →
Continuity (3)
Provisional Application 63376338 · Sep 20, 2022
Provisional Application 63301907 · Jan 21, 2022
Related Publication 20230234952A1 · Jul 27, 2023
Cited By (2)
US 12,384,780 US 12,421,241